Method and device for monitoring and treatment of seasonal affective disorder

Patent metadata

Field	Value
Publication number	US-9289623-B2
Application number	US-201313833196-A
Country	US
Kind code	B2
Filing date	Mar 15, 2013
Priority date	Mar 15, 2013
Publication date	Mar 22, 2016
Grant date	Mar 22, 2016

Abstract

This invention provides for an energized biomedical ophthalmic device and associated method of measuring changes in biomarkers contained in tear film to generate data related to a light therapy regimen used to treat symptoms associated with seasonal affective disorder. In some embodiments, the energized biomedical ophthalmic device can include an energized contact lens with a light source in communication with a processor controlling said light source according to the light therapy regimen. The light therapy regimen may be generated or modified by the processor from the measured changes and sometimes from user's preferences, and/or additional measurements, including for example, light exposure and/or circadian rhythm of the user.

First claim

The invention claimed is:

1. An energized biomedical ophthalmic device capable of residing in or on an eye of a user, comprising:
a body selected from the group consisting of an energized contact lens, intraocular lens, overlay lens, ocular insert and punctal plug, wherein the body comprises:
an energy source;
a light source configured to emit light for the treatment of a seasonal affective disorder of the user, energized by the energy source and positioned to direct the light towards the eye of the user;
a biomarker sensor configured to detect changes in biomolecules contained in the tear film of the user and generate signal data corresponding to the detected changes, wherein the biomolecules are selected from the group consisting of serotonin, melatonin and Interleukin-6;
a processor in logical communication with the biomarker sensor, wherein the processor is configured to receive and process said signal data and to control the light source.

2. The energized biomedical ophthalmic device of claim 1 , additionally comprising a light sensor in communication with the processor.

3. The energized biomedical ophthalmic device of claim 1 , wherein the biomarker sensor comprises an electrochemical microchip with analytical sensitivity.

4. The energized biomedical ophthalmic device of claim 3 , wherein the electrochemical microchip with analytical sensitivity is configured to measuring changes of melatonin biomolecules in tear film.

5. The energized biomedical ophthalmic device of claim 3 , wherein the electrochemical microchip with analytical sensitivity is configured to measuring changes of serotonin biomolecules in tear film.

6. The energized biomedical ophthalmic device of claim 3 , wherein the electrochemical microchip with analytical sensitivity is configured to measuring changes of interleukin-6 biomolecules in tear film.

7. The energized biomedical ophthalmic device of claim 1 , wherein the body is an energized contact lens.

8. The energized biomedical ophthalmic device claim 7 , wherein the energized contact lens comprises a media insert encapsulating the energy source.

9. The energized biomedical ophthalmic device claim 1 , additionally comprising an antenna.

10. The energized biomedical ophthalmic device claim 9 , wherein the antenna can transmit electrical signals from an exterior controller.

11. The energized biomedical ophthalmic device claim 1 , wherein the light source comprises one or more light-emitting diodes.

Assignees

• Johnson & Johnson Vision Care

Inventors

• Pugh Randall B
• Flitsch Frederick A

Classifications

• A61B5/002

  Monitoring the patient using a local or closed circuit, e.g. in a room or building (A61B5/0017 takes precedence) · CPC title

• A61B5/165

  Evaluating the state of mind, e.g. depression, anxiety · CPC title

• A61N2005/0652

  Arrays of diodes · CPC title

• A61B5/4836 Primary

  Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence) · CPC title

• A61B5/14546

  for measuring analytes not otherwise provided for, e.g. ions, cytochromes · CPC title