System and method for automated titration of continuous positive airway pressure using an obstruction index

Patent metadata

Field	Value
Publication number	US-9289566-B2
Application number	US-24012405-A
Country	US
Kind code	B2
Filing date	Sep 30, 2005
Priority date	Jun 4, 2004
Publication date	Mar 22, 2016
Grant date	Mar 22, 2016

Abstract

Described is a system including an air pressure supply arrangement, a sensor and a titration device. The air pressure supply arrangement provides air pressure to a patient's airways. The sensor detects input data corresponding to a patient's breathing patterns of a plurality of breaths. The titration device receives and analyzes the input data to determine existence of breathing disorder and corresponding characteristics. The titration device generates output data for adjusting the air pressure supplied to the patient as a function of an index of abnormal respiratory events included in the input data.

First claim

What is claimed is:

1. A system, comprising:
an air pressure supply arrangement providing air pressure to a patient's airways;
a sensor detecting input data corresponding to a patient's breathing patterns of a plurality of breaths; and
a titration device receiving and analyzing the input data to determine existence of breathing disorder and corresponding characteristics, the titration device generating output data for adjusting the air pressure supplied to the patient as a function of an index of abnormal respiratory events included in the input data, wherein the index includes a number of the abnormal respiratory events in a time period.

2. The system according to claim 1 , wherein the abnormal respiratory events include at least one of an apnea, a hypopnea, an event of upper airway resistance, snoring and a flow limitation.

3. The system according to claim 1 , wherein the output data is one of a predetermined pressure adjustment algorithm, a single value pressure and a varying pressure function.

4. The system according to claim 1 , wherein the input data is obtained for at least one time period prior to generating the output data.

5. The system according to claim 1 , wherein, when the number for at least one time period surpasses a preset value, the titration device increases the pressure.

6. The system according to claim 5 , wherein, when the number for the at least one time period is less than the preset value, the titration device does one of (i) maintains the pressure and (ii) decreases the pressure.

7. The system according to claim 1 , wherein the index includes at least one of (i) a number of apneas and hypopneas, (ii) a number of flow limitations and (iii) and a time the patient is in a sustained flow limitation state.

8. The system according to claim 7 , wherein the titration device adjusts the sum number by a factor indicative of a time the patient is in a flow limitation state.

9. The system according to claim 8 , wherein the factor is ⅓.

10. A method, comprising:
activating a titration device;
obtaining input data by the titration device from a sensor, the input data corresponding to a patient's breathing patterns;
determining with the titration device existence in the input data of one of a breathing disorder and an abnormal flow limitation and corresponding characteristics; and
generating using the titration device an output data as a function of an index of abnormal respiratory events included in the input data, wherein the index includes a number of the abnormal respiratory events in a time period.

11. The method according to claim 10 , further comprising:
supplying a pressure to a patient's airway.

12. The method according to claim 11 , further comprising:
adjusting a pressure supplied to a patient as a function of the output data.

13. The method according to claim 12 , wherein the generating step includes the following substeps:
when the index of the breathing disorders is lower than a predefined value, generating the output data to decrease the pressure; and
when the index of the breathing disorders is greater than a predefined value generating the output data to increase the pressure.

14. The method according to claim 10 , wherein the abnormal respiratory events include at least one of an apnea, a hypopnea, an event of upper airway resistance, snoring and a flow limitation.

15. The method according to claim 10 , wherein the output data is one of a predetermined pressure adjustment algorithm, a single value pressure and a varying pressure function.

16. The method according to claim 10 , wherein the input data is obtained for at least one time period prior to generating the output data.

17. The method according to claim 12 , wherein the number of the abnormal respiratory events is obtained for the at least one time period.

18. The method according to claim 17 , wherein, when the number for the at least one time period surpasses a preset value, increasing the pressure.

19. The method according to claim 17 , wherein, when the number for the at least one time period is less than the preset value, one of:
maintaining the pressure; and
decreasing the pressure.

20. The method according to claim 10 , wherein the index includes at least one of (i) a number of apneas and hypopneas, (ii) a number of flow limitations and (iii) a time the patient is in a sustained flow limitation state.

21. The method according to claim 17 , further comprising:
adjusting, by the titration device, the number by a factor indicative of a time the patient is in a flow limitation state.

22. A device, comprising:
a processor;
a memory; and
a titration module obtaining input data from a sensor, the input data corresponding to a patient's breathing patterns, the titration module determining an existence in the input data of one of a breathing disorder and an abnormal flow limitation and corresponding characteristics, the titration module generating an output data as a function of an index of abnormal respiratory events included in the input data, wherein the index includes a number of the abnormal respiratory events in a time period.

Assignees

• Ayappa Indu A
• Norman Robert G
• Rapoport David M
• Univ New York

Inventors

• Ayappa Indu A
• Norman Robert G
• Rapoport David M

Classifications

• A61M16/10 Primary

  Preparation of respiratory gases or vapours · CPC title

• A61M16/0069

  the speed thereof being controlled by respiratory parameters, e.g. by inhalation · CPC title

• A61M16/0431

  with a cross-sectional shape other than circular · CPC title

• A61M2016/0021

  with a proportional output signal, e.g. from a thermistor · CPC title

• A61M16/0051 Primary

  with alarm devices · CPC title