Inhaler with indexing linked to movement of cover

Patent metadata

Field	Value
Publication number	US-9289565-B2
Application number	US-200913123140-A
Country	US
Kind code	B2
Filing date	Oct 7, 2009
Priority date	Oct 8, 2008
Publication date	Mar 22, 2016
Grant date	Mar 22, 2016

Abstract

The disclosure relates to a medical dispenser, comprising an outlet and a plurality of sealed compartments containing medicament to be sequentially aligned with and dispensed through said outlet. Movement of an actuator sequentially causes mechanical energy to be built up and then released and converted into an indexing movement of the compartments. The disclosure also relates to an indexing method for a medical dispenser.

First claim

The invention claimed is:

1. A medical dispenser, comprising:
an outlet;
a plurality of sealed compartments configured to contain medicament to be sequentially aligned with and dispensed through said outlet;
an actuator movable between a first position and a second position, wherein movement of the actuator from the first position towards the second position causes mechanical energy to be built up, and wherein the arrival of the actuator at the second position causes the built-up mechanical energy to be released and converted into an indexing movement of the compartments;
a track configured to move with the actuator;
an indexing mechanism for sequentially aligning the compartments with the outlet, wherein the indexing mechanism is operatively connected to the actuator, wherein said mechanical energy is built up in the indexing mechanism;
a counteracting member having a counteracting position, in which the counteracting member temporarily prevents said mechanical energy from being released, and a release position, in which the mechanical energy is released whereby the indexing mechanism is allowed to advance the compartments, wherein the counteracting member is operatively connected to the actuator such that the counteracting member reaches said release position when the actuator reaches said second position, wherein the counteracting member includes a brake configured to prevent the compartments from moving and a follower connected to the brake and configured to travel along said track in response to the movement of the actuator, wherein, when the follower reaches a point of release, the connected brake is released.

2. The medical dispenser of claim 1 , wherein, in said counteracting position, the counteracting member is in a fixating contact with one or more compartments or with a structure carrying the compartments.

3. The medical dispenser of claim 1 , further comprising a rotatable disk holding said compartments, wherein, in said counteracting position, the counteracting member engages the disk to prevent it from rotating.

4. The medical dispenser of claim 1 , further comprising a stop element which, during said indexing movement, is configured to engage with the compartments or a structure carrying the compartments in order to limit said movement.

5. The medical dispenser of claim 1 , wherein said indexing mechanism comprises a spring in which said mechanical energy is built up.

6. The medical dispenser of claim 5 , wherein said indexing mechanism comprises a drive member which is engagable with the compartments or a structure carrying the compartments, the drive member being connected to the spring so that when the counteracting member reaches said release position, the accumulated mechanical energy in the spring is transmitted via the drive member to the compartments.

7. The medical dispenser of claim 1 , wherein said actuator comprises an outlet cover configured to open and close said outlet.

8. The medical dispenser of claim 7 , wherein said movement of the actuator from the first position towards the second position involves a movement of the outlet cover towards closing the outlet.

9. The medical dispenser of claim 1 , wherein the medical dispenser is an inhaler.

10. The medical dispenser of claim 9 , wherein the medicament comprises an active ingredient including one or more of mometasone; ipratropium bromide; tiotropium and salts thereof; salemeterol; fluticasone propionate; beclomethasone dipropionate; reproterol; clenbuterol, rofleponide and salts; nedocromil; sodium cromoglycate; flunisolide; budesonide; formoterol fumarate dihydrate; terbutaline; terbutaline sulphate; salbutamol base and sulphate; fenoterol; 3-[2-(4-Hydroxy-2-oxo-3H-1,3-benzothiazol-7-yl)ethylamino]-N-[2-[2-(4-methylphenyl)ethoxy]ethyl]propane-sulphonamide; hydrochloride; indacaterol; aclidinium bromide; N-[2-(Diethylamino)ethyl]-N-(2-{[2-(4-hydroxy-2-oxo-2,3-dihydro-1,3-benzothiazol-7-yl)ethyl]amino}ethyl)-3-[2-(1-naphthyl)ethoxy]propanamide or a pharmaceutically acceptable salt thereof (e.g., dihydrobromide); N-Cyclohexyl-N 3 -[2-(3-fluorophenyl)ethyl]-N-(2-{[2-(4-hydroxy-2-oxo-2,3-dihydro-1,3-benzothiazol-7-yl)ethyl]amino}ethyl)-β-alaninamide or a pharmaceutically acceptable salt thereof (e.g., di-D-mandelate); a [2-(4-Chloro-benzyloxy)-ethyl]-[2-((R)-cyclohexyl-hydroxy-phenyl-methyl)-oxazol-5-ylmethyl]-dimethyl-ammonium salt (e.g., hemi-naphthalene-1,5-disulfonate); and a (R)-1-[2-(4-Fluoro-phenyl)-ethyl]-3-((S)-2-phenyl-2-piperidin-1-yl-propionyloxy)-1-azonia-bicyclo[2.2.2]octane salt (e.g., bromide or toluenesulfonate).

11. A medical dispenser, comprising:
an outlet;
a plurality of compartments;
an actuator, wherein movement of the actuator from a first position towards a second position causes mechanical energy to be built up, and wherein the arrival of the actuator at the second position causes the built-up mechanical energy to be released and converted into an indexing movement of the compartments;
a track configured to move with the actuator;
an indexing mechanism for sequentially aligning the compartments with the outlet; and
a counteracting member having a counteracting position, in which the counteracting member prevents the release of the mechanical energy, and a release position, in which the mechanical energy is released whereby the indexing mechanism is allowed to advance the compartments, wherein the counteracting member includes a brake configured to prevent the compartments from moving and a follower connected to the brake and configured to travel along said track in response to the movement of the actuator, wherein, when the follower reaches a point of release, the connected brake is released.

12. The medical dispenser of claim 11 , wherein said indexing mechanism comprises a spring in which said mechanical energy is built up.

13. The medical dispenser of claim 11 , wherein, in said counteracting position, the counteracting member is in a fixating contact with one or more compartments or with a structure carrying the compartments.

14. The medical dispenser of claim 11 , further comprising a rotatable disk holding said compartments, wherein, in said counteracting position, the counteracting member engages the disk to prevent it from rotating.

15. The medical dispenser of claim 11 , further comprising a stop element which, during said indexing movement, is configured to engage with the compartments or a structure carrying the compartments in order to limit said movement.

Assignees

• Briant John
• Campbell Patrick
• Cooke Charles
• Groombridge Christopher
• John James Daniel
• Penhallurick Trevor John
• Bakewell William
• Harrison Nicholas
• Astrazeneca Ab

Inventors

• Briant John
• Campbell Patrick
• Cooke Charles
• Groombridge Christopher
• John James Daniel
• Penhallurick Trevor John
• Bakewell William
• Harrison Nicholas

Classifications

• A61M15/0043

  Non-destructive separation of the package, e.g. peeling · CPC title

• A61M15/0026

  Hinged caps · CPC title

• A61M15/0003

  with means for dispensing more than one drug · CPC title

• A61M15/0045 Primary

  using multiple prepacked dosages on a same carrier, e.g. blisters · CPC title

• A61M15/0048

  the dosages being arranged in a plane, e.g. on diskettes · CPC title