Robotic Microtool Control in an Intelligent Automated In Vitro Fertilization and Intracytoplasmic Sperm Injection Platform
US-2024426856-A1 · Dec 26, 2024 · US
US9286673B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9286673-B2 |
| Application number | US-201314044990-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 3, 2013 |
| Priority date | Oct 5, 2012 |
| Publication date | Mar 15, 2016 |
| Grant date | Mar 15, 2016 |
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The invention relates generally systems for correcting distortion in a medical image and methods of use thereof. Methods and systems for displaying a medical image of a lumen of a biological structure, generally comprise obtaining image data of a lumen of a biological structure from an imaging device, correcting the image data for translational distortions, in which correcting is accomplished without reference to another data set, and displaying a corrected image.
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What is claimed is: 1. A method for displaying a medical image of a lumen of a biological structure, the method comprising providing at least one computer-readable medium having instructions stored thereon which, when executed by a computing device, cause the computing device to carry out operations comprising: obtaining image data of a lumen of a biological structure from an imaging device; correcting the image data for translational distortions, wherein correcting is accomplished without reference to another data set and wherein correcting comprises compensating for device angular distortion, wherein compensating comprises: aligning a reference position of a first frame with a catheter center position of a neighboring frame; determining a longitudinal distance between neighboring frames; evaluating an angle between two vectors, wherein a first vector is defined by a distance between a reference position in a first frame and a catheter center position in a neighboring frame, and a second vector is defined by a distance between a reference position in a first frame and a reference position in said neighboring frame; and rotating the neighboring frame about an axis through a value corresponding to the angle between the said two vectors, wherein said axis is located in a plane defined by the neighboring frame, intersecting the catheter center position of the neighboring frame, and oriented perpendicular to a plane in which said first vector and second vector are located; and displaying a corrected image. 2. The method of claim 1 , wherein the structure is a vessel. 3. The method of claim 1 , wherein the image data is selected from the group consisting of splayed image data, image longitudinal display (ILD) data, three dimensional image data, tomographic image data, and a combination thereof. 4. The method of claim 3 , wherein the medical imaging device comprises an optical coherence tomography (OCT) catheter and the image data is OCT image data. 5. The method of claim 1 , wherein the translational distortions are selected from the group consisting of frame alignment distortion, device angular distortion, helical offset distortion, and a combination thereof. 6. The method of claim 1 , wherein correcting comprises compensating for frame alignment distortions. 7. The method of claim 6 , wherein compensating comprises: identifying a reference position in each frame of the image data; and aligning each frame using the reference position. 8. The method of claim 7 , further comprising: aligning reference positions in all neighboring frames; and calculating a new reference position from the aligned frames. 9. The method of claim 7 , wherein the reference position is a lumen center. 10. The method of claim 7 , wherein identifying further comprises: fitting a geometric shape to a lumen border; calculating a reference position within the area circumscribed by the geometric shape; and aligning the image center to the reference position. 11. The method of claim 10 , wherein the geometric shape is a centroid, a circle, or an ellipse. 12. The method of claim 10 , wherein the reference position is smoothed across all image frames. 13. A method for displaying a medical image of a lumen of a biological structure, the method comprising providing at least one computer-readable medium having instructions stored thereon which, when executed by a computing device, cause the computing device to carry out operations comprising: obtaining image data of a lumen of a biological structure from an imaging device; correcting the image data for translational distortions, wherein correcting is accomplished without reference to another data set and wherein correcting comprises compensating for helical offset distortion, wherein compensating comprises: evaluating the longitudinal displacement for a 360° set of image data points; and interpolating data points to lie in a plane perpendicular to the direction of longitudinal displacement, wherein said interpolation is proportional to an angular coordinate and corresponding longitudinal coordinate for each data point in a 360° image scan; and displaying a corrected image. 14. A system for displaying a medical image of a lumen of a biological structure, the system comprising a monitor to display an image of the lumen of the biological structure, a central processing unit (CPU), and storage coupled to the CPU for storing instructions that configure the CPU to: obtain image data of a lumen of a biological structure from an imaging device; correct the image data for translational distortions, wherein correcting is accomplished without reference to another data set and wherein to correct comprises compensating for device angular distortion, wherein compensating comprises: aligning a reference position of a first frame with a catheter center position of a neighboring frame; determining a longitudinal distance between neighboring frames; evaluating an angle between two vectors, wherein a first vector is defined by a distance between a reference position in a first frame and a catheter center position in a neighboring frame, and a second vector is defined by a distance between a reference position in a first frame and a reference position in said neighboring frame; and rotating the neighboring frame about an axis through a value corresponding to the angle between the said two vectors, wherein said axis is located in a plane defined by the neighboring frame, intersecting the catheter center position of the neighboring frame, and oriented perpendicular to a plane in which said first vector and second vector are located; and display a corrected image. 15. The system of claim 14 , wherein the structure is a vessel. 16. The system of claim 15 , wherein the image data is selected from the group consisting of splayed image data, image longitudinal display (ILD) data, three dimensional image data, tomographic image data, and a combination thereof. 17. The system of claim 16 , wherein the medical imaging device comprises an optical coherence tomography (OCT) catheter and the image data is OCT image data. 18. The system of claim 14 , wherein the translational distortions are selected from the group consisting of frame alignment distortion, device angular distortion, helical offset distortion, and a combination thereof. 19. The system of claim 14 , wherein to correct comprises compensating for frame alignment distortions. 20. The system of claim 19 , wherein compensating comprises: identifying a reference position in each frame of the image data; and aligning each frame using the reference point. 21. The system of claim 20 , further comprising: aligning reference positions all neighboring frames; and calculating a new reference position from the aligned frames. 22. The system of claim 20 , wherein the reference position is a lumen center. 23. The system of claim 20 , wherein identifying further comprises: fitting a geometric shape to a lumen border; calculating a reference position within the area circumscribed by the geometric shape; and aligning the image center to the reference position. 24. The system of claim 23 , wherein the geometric shape is a centroid, a circle, or an ellipse. 25. The system of claim 23 , wherein the reference position is smoothed across all image frames. 26. A system for displaying a medical image of a lumen of a biological structure,
Biomedical image inspection · CPC title
Geometric correction · CPC title
Blood vessel; Artery; Vein; Vascular · CPC title
Optical tomography; Optical coherence tomography [OCT] · CPC title
Physics · mapped topic
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