Bordetella outer-membrane protein antigens and methods of making and using the same

US9283268B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9283268-B2
Application numberUS-201414498537-A
CountryUS
Kind codeB2
Filing dateSep 26, 2014
Priority dateOct 25, 2007
Publication dateMar 15, 2016
Grant dateMar 15, 2016

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

An isolated protein or peptide selected from the group consisting of Bordetella colonization factor A (BcfA) protein and antigenic fragments thereof is described, along with an isolated nucleic acid encoding the same, antibodies that bind to the same, methods of producing an immune response in a mammalian subject in need thereof by administering the proteins, peptides or antibodies, and pharmaceutical compositions comprising the same.

First claim

Opening claim text (preview).

That which is claimed is: 1. A method of treating a mammalian subject for a Bordetella infection, comprising administering said subject an antibody in a treatment effective amount, wherein said antibody binds to Bordetella colonization factor A (BcfA) protein fragment consisting of 20 to 500 consecutive amino acids of either SEQ ID NO: 2 or SEQ ID NO:3. 2. The method of claim 1 , wherein said Bordetella infection is a Bordetella bronchiseptica or Bordetella pertussis infection. 3. The method of claim 1 , wherein said Bordetella infection is a Bordetella bronchiseptica infection. 4. The method of claim 1 , wherein said Bordetella infection is a Bordetella pertussis infection.

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What does patent US9283268B2 cover?
An isolated protein or peptide selected from the group consisting of Bordetella colonization factor A (BcfA) protein and antigenic fragments thereof is described, along with an isolated nucleic acid encoding the same, antibodies that bind to the same, methods of producing an immune response in a mammalian subject in need thereof by administering the proteins, peptides or antibodies, and pharm…
Who is the assignee on this patent?
Univ Wake Forest Health Sciences
What technology area does this patent fall under?
Primary CPC classification A61K39/099. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Mar 15 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).