Topical otic, ophthalmic, and nasal corticosteroid formulations
US-2024000801-A1 · Jan 4, 2024 · US
US9283232B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9283232-B2 |
| Application number | US-201314402548-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 3, 2013 |
| Priority date | Jun 14, 2012 |
| Publication date | Mar 15, 2016 |
| Grant date | Mar 15, 2016 |
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Provided is a dry powder for inhalation formulation comprising salmeterol xinafoate, fluticasone propionate and tiotropium bromide, as pharmaceutically active ingredients, and a carrier, and an inhalation formulation comprising same. The inventive dry powder inhalation formulation having good content uniformity and showing small changes in the aerodynamic size distribution in accordance with the flow rate changes can effectively deliver said pharmaceutically active ingredients to a target site upon administration, and thus can be useful in the prevention or treatment of respiratory diseases, particularly asthma and COPD.
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What is claimed is: 1. A dry powder for inhalation formulation comprising salmeterol xinafoate, fluticasone propionate, tiotropium bromide, and a carrier, said powder having an average particle size in a range of 30 to 120 μm. 2. The dry powder for inhalation formulation of claim 1 , whose average particle size is in a range of 55 to 65 μm. 3. The dry powder for inhalation formulation of claim 1 , wherein the carrier is selected from the gr…
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