Compressed chewing gum tablet

Patent metadata

Field	Value
Publication number	US-9283191-B2
Application number	US-201314090857-A
Country	US
Kind code	B2
Filing date	Nov 26, 2013
Priority date	Dec 20, 2007
Publication date	Mar 15, 2016
Grant date	Mar 15, 2016

Abstract

A compressed chewing gum tablet includes at least a first and a second chewing gum module, the first chewing gum module including a first chewing gum composition including at least a first active ingredient and chewing gum granules containing gum base, the second chewing gum module including a second chewing gum composition including at least a second active ingredient and chewing gum granules containing gum base, wherein the first active ingredient is a pharmaceutically active ingredient, and the second active ingredient is selected from the group consisting of pharmaceutically active ingredients and enhancers, wherein the gum base content of the first and second chewing gum modules is different.

First claim

What is claimed is:

1. A compressed chewing gum tablet comprising at least a first and a second chewing gum module,
said first chewing gum module comprising a first chewing gum composition comprising at least a first active ingredient and chewing gum granules containing gum base,
said second chewing gum module comprising a second chewing gum composition comprising at least a second active ingredient and chewing gum granules containing gum base,
wherein the first chewing gum composition is different in composition than the second chewing gum composition,
wherein said first active ingredient is nicotine and said second active ingredient is an enhancer; and
wherein at least part of the enhancer is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module, and wherein nicotine is contained within said chewing gum granules of the first chewing gum module.

2. The compressed chewing gum tablet of claim 1 wherein substantially all of the nicotine is contained within said chewing gum granules of the first chewing gum module.

3. The compressed chewing gum tablet of claim 1 wherein substantially all of the enhancer is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module.

4. The compressed chewing gum tablet of claim 1 , wherein said first chewing gum composition comprises a further active ingredient different from the nicotine.

5. The compressed chewing gum tablet of claim 1 , wherein said second chewing gum composition comprises a further active ingredient different from the enhancer.

6. The compressed chewing gum tablet of claim 1 , wherein some of the enhancer in said second chewing gum module is contained within the chewing gum granules of the second chewing gum module.

7. The compressed chewing gum tablet of claim 1 , wherein said compressed chewing gum tablet comprises at least three individual coherent compressed modules.

8. A compressed chewing gum tablet comprising at least a first and a second chewing gum module,
said first chewing gum module comprising a first chewing gum composition comprising at least a first active ingredient and chewing gum granules containing gum base,
said second chewing gum module comprising a second chewing gum composition comprising at least a second active ingredient and chewing gum granules containing gum base,
wherein the first chewing gum composition is different in composition than the second chewing gum composition,
wherein said first active ingredient is nicotine and said second active ingredient is a pH control agent; and
wherein at least part of the pH control agent is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module.

9. The compressed chewing gum tablet of claim 8 wherein substantially all of the pH control agent is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module.

10. The compressed chewing gum tablet of claim 8 , wherein some of the pH control agent in said second chewing gum module is contained within the chewing gum granules of the second chewing gum module.

11. A compressed chewing gum tablet comprising at least a first and a second chewing gum module,
said first chewing gum module comprising a first chewing gum composition comprising at least a first active ingredient and chewing gum granules containing gum base,
said second chewing gum module comprising a second chewing gum composition comprising at least a second active ingredient and chewing gum granules containing gum base,
wherein the first chewing gum composition is different in composition than the second chewing gum composition,
wherein said first active ingredient is nicotine and said second active ingredient is an enhancer; and
wherein at least part of the enhancer is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module.

12. The compressed chewing gum tablet of claim 11 wherein substantially all of the enhancer is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module.

13. The compressed chewing gum tablet of claim 11 , wherein some of the enhancer in said second chewing gum module is contained within the chewing gum granules of the second chewing gum module.

14. A compressed chewing gum tablet comprising at least a first and a second chewing gum module,
said first chewing gum module comprising a first chewing gum composition comprising at least a first active ingredient and chewing gum granules containing gum base,
said second chewing gum module comprising a second chewing gum composition comprising at least a second active ingredient and chewing gum granules containing gum base,
wherein the first chewing gum composition is different in composition than the second chewing gum composition,
wherein said first active ingredient is a pharmaceutically active ingredient and said second active ingredient is an enhancer; and
wherein at least part of the enhancer is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module, and wherein the pharmaceutically active ingredient is contained within said chewing gum granules of the first chewing gum module.

15. The compressed chewing gum tablet of claim 14 wherein the enhancer comprises a pH control agent.

16. The compressed chewing gum tablet of claim 14 wherein substantially all of the enhancer is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module.

17. The compressed chewing gum tablet of claim 14 , wherein some of the enhancer in said second chewing gum module is contained within the chewing gum granules of the second chewing gum module.

18. The compressed chewing gum tablet of claim 14 , wherein some of the enhancer in said second chewing gum module is contained within the chewing gum granules of the second chewing gum module.

19. A compressed chewing gum tablet comprising at least a first and a second chewing gum module,
said first chewing gum module comprising a first chewing gum composition comprising at least a first active ingredient and chewing gum granules containing gum base,
said second chewing gum module comprising a second chewing gum composition comprising at least a second active ingredient and chewing gum granules containing gum base,
wherein the first chewing gum composition is different in composition than the second chewing gum composition,
wherein said first active ingredient is a pharmaceutically active ingredient and said second active ingredient is an enhancer; and
wherein at least part of the enhancer is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module.

20. The compressed chewing gum tablet of claim 19 wherein the enhancer comprises a pH control agent.

Assignees

• Andersen Carsten
• Lorenzen Gitte
• Arent Nicolai
• Thorengaard Bitten
• Wittorff Helle
• Fertin Pharma As

Inventors

• Andersen Carsten
• Lorenzen Gitte
• Arent Nicolai
• Thorengaard Bitten
• Wittorff Helle

Classifications

• A61K9/0058

  Chewing gums (non-medicinal aspects, preparing chewing gum A23G4/00; chewing gum for care of the teeth or oral cavity, e.g. with breath freshener A61Q11/00) · CPC title

• A61K9/2077

  Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets · CPC title

• A61K31/465

  Nicotine; Derivatives thereof · CPC title

• A61K9/146

  with organic macromolecular compounds · CPC title

• A23G4/12

  containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins (containing dairy products A23G4/16) · CPC title