Metallic-nanofinger device for chemical sensing

Patent metadata

Field	Value
Publication number	US-9274058-B2
Application number	US-201013879245-A
Country	US
Kind code	B2
Filing date	Oct 20, 2010
Priority date	Oct 20, 2010
Publication date	Mar 1, 2016
Grant date	Mar 1, 2016

Abstract

A metallic-nanofinger device for chemical sensing. The device includes a substrate, and a plurality of nanofingers. A nanofinger includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger are to self-arrange into a close-packed configuration with at least one analyte molecule disposed between at least the metallic cap and a second metallic cap of respective nanofinger and second nanofinger. A morphology of the metallic cap is to generate a shifted plasmonic-resonance peak associated with amplified luminescence from the analyte molecule. A coating encapsulating the metallic cap to respond upon exposure to a liquid, and a chemical-sensing chip including the metallic-nanofinger device are also provided.

First claim

What is claimed is:

1. A metallic-nanofinger device for chemical sensing, said device comprising:
a substrate; and
a plurality of nanofingers coupled with said substrate, a nanofinger of said plurality of nanofingers comprising:
a flexible column;
a metallic cap coupled to an apex of said flexible column; and
a coating encapsulating said metallic cap,
wherein at least said nanofinger and a second nanofinger of said plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule disposed between at least said metallic cap and a second metallic cap of respective nanofinger and second nanofinger, wherein a morphology of said metallic cap is to generate a shifted plasmonic-resonance peak associated with amplified luminescence from said analyte molecule, and wherein said coating is to develop a response upon exposure to a liquid.

2. The metallic nanofinger device of claim 1 , wherein said plasmonic-resonance peak associated with luminescence from said analyte molecule is shifted towards longer wavelengths.

3. The metallic nanofinger device of claim 1 , wherein said plasmonic-resonance peak associated with luminescence from said analyte molecule is shifted towards shorter wavelengths.

4. The metallic-nanofinger device of claim 1 , wherein said morphology of said metallic cap as measured by a roughness average of a surface roughness of said metallic cap is such that said roughness average is less than about 5 nanometers (nm).

5. The metallic-nanofinger device of claim 1 , wherein said morphology of said metallic cap as measured by a shape parameter of said metallic cap is such that said shape parameter varies from metallic cap to metallic cap of respective metallic nanofingers by no more than between plus 10 nm to minus 10 nm from an average value of said shape parameter.

6. The metallic-nanofinger device of claim 5 , wherein said morphology of said metallic cap is substantially spherical, and said shape parameter comprises an average radius of said metallic cap.

7. The metallic-nanofinger device of claim 5 , wherein said morphology of said metallic cap is truncated substantially spherical, and said shape parameter comprises an average radius of said metallic cap.

8. A metallic-nanofinger device for chemical sensing, said device comprising:
a substrate; and
a plurality of nanofingers coupled with said substrate, a nanofinger of said plurality of nanofingers comprising:
a flexible column;
a metallic cap coupled to an apex of said flexible column; and
a coating encapsulating said metallic cap,
wherein at least said nanofinger and a second nanofinger of said plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule disposed between at least said metallic cap and a second metallic cap of respective nanofinger and second nanofinger, and
wherein said coating is to develop a response upon exposure to a liquid.

9. The metallic-nanofinger device of claim 8 , wherein said liquid comprises a solute; said solute comprises said analyte molecule; and, said coating has an affinity to react with said analyte molecule.

10. The metallic-nanofinger device of claim 8 , wherein said coating comprises properties enabling said coating to dissolve via interacting with a solvent of said liquid.

11. The metallic-nanofinger device of claim 10 , wherein said liquid further comprises a solute; said solute comprises said analyte molecule; said coating has an affinity to react with said analyte molecule; and, wherein said analyte molecule is left bound to said metallic cap.

12. The metallic-nanofinger device of claim 8 , wherein said coating comprises properties such that said coating does not dissolve via interaction with said liquid.

13. The metallic-nanofinger device of claim 12 , wherein said liquid further comprises a solute; said solute comprises said analyte molecule; said coating has an affinity to react with said analyte molecule; and, wherein said analyte molecule is left bound to said coating encapsulating said metallic cap.

14. The metallic-nanofinger device of claim 8 , wherein said coating comprises a substance selected from tile group consisting of polymethylmethacrylate, a compound soluble in a solvent, a compound insoluble in a solvent, at least one antibody, at least one antigen, at least one deoxyribonucleic acid segment, at least one ribonucleic acid segment, at least one protein, at least one protein segment, substances to develop a response upon exposure to said liquid, and substances to develop a response upon exposure to an analyte molecule in said liquid.

15. A chemical-sensing chip, comprising:
a metallic-nanofinger device for chemical sensing, said device comprising:
a substrate; and
an array of patches, a patch of said array comprising:
a plurality of nanofingers coupled with said substrate, a nanofinger of said plurality of nanofingers comprising:
a flexible column; and
a metallic cap coupled to an apex of said flexible column; and
a coating encapsulating said metallic cap;
wherein at least said nanofinger and a second nanofinger of said plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule disposed between at least said metallic cap and a second metallic cap of respective nanofinger and second nanofinger; and
wherein said coating of said metallic cap in said patch is functionalized with a certain probe molecule to develop a specific response upon exposure to certain targets in a liquid comprising said targets in a complex analyte solution.

Assignees

• Li Zhiyong
• Williams R Stanley
• Hewlett Packard Development Co

Inventors

• Li Zhiyong
• Williams R Stanley

Classifications

• G01N21/658 Primary

  enhancement Raman, e.g. surface plasmons · CPC title

• G01N21/648

  using evanescent coupling or surface plasmon coupling for the excitation of fluorescence · CPC title