Lactobacillus paracasei strain
US-12152232-B2 · Nov 26, 2024 · US
Strain of L. bulgaricus capable of inhibiting the adhesion of H. pylori strains to epithelial cells
US9272007B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9272007-B2 |
| Application number | US-201114237740-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 9, 2011 |
| Priority date | Aug 9, 2011 |
| Publication date | Mar 1, 2016 |
| Grant date | Mar 1, 2016 |
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Abstract
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The present invention relates to a new strain of Lactobacillus delbrueckii subsp. bulgaricus , suitable for use in the treatment or prevention of Helicobacter pylori infection.
First claim
Opening claim text (preview).
The invention claimed is: 1. A genetically transformed Lactobacillus delbrueckii subsp. bulparicus ( L. bulparicus ) strain derived from the parent strain Lactobacillus bulparicus deposited with the Collection Nationale De Cultures De Microorganismes (CNCM) under accession number I-4428, wherein one or more endogenous gene(s) of the parent strain are mutated and/or one or more gene(s) of interest are transformed into the parent strain, wherein said genetically transformed L. bulparicus strain is capable of inhibiting adhesion of Helicobacter pylori strains to epithelial cells. 2. A cell fraction obtained by a method comprising: (a) culturing a L. bulparicus strain, wherein the L. bulparicus strain is (i) a L. bulparicus strain deposited with the CNCM under Accession number I-4428, or (ii) a genetically transformed L. bulparicus strain of claim 1 , and (b) isolating the cell fraction from the culture in step a), wherein said cell fraction inhibits the adhesion of H. pylori strains to epithelial cells. 3. A fermented dairy product composition comprising a Lactobacillus delbrueckii subsp. bulgaricus strain deposited with the CNCM under Accession number I-4428 or a genetically transformed L. bulgaricus strain of claim 1 . 4. The composition according to claim 3 , comprising at least 10 5 cfu per gram dry weight of the L. bulgaricus strain. 5. The composition according to claim 3 , wherein the composition is a nutritional composition. 6. The composition according to claim 5 , wherein the composition is a yogurt product. 7. A composition comprising the cell fraction according to claim 2 . 8. The composition according to claim 7 , wherein the composition is a nutritional composition. 9. The composition according to claim 8 , wherein the composition is a dairy product. 10. A pharmaceutical composition comprising the cell fraction according to claim 2 . 11. The composition according to claim 4 , comprising at least 10 6 cfu per gram dry weight of the L. bulgaricus strain.
Assignees
Inventors
Classifications
Antibacterial agents · CPC title
- A61K35/747Primary
Lactobacilli, e.g. L. acidophilus or L. brevis · CPC title
Function of food ingredients · CPC title
- A23C9/1238Primary
using specific L. bulgaricus or S. thermophilus microorganisms; using entrapped or encapsulated yoghurt bacteria; Physical or chemical treatment of L. bulgaricus or S. thermophilus cultures; Fermentation only with L. bulgaricus or only with S. thermophilus · CPC title
Drugs for disorders of the alimentary tract or the digestive system · CPC title
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- What does patent US9272007B2 cover?
- The present invention relates to a new strain of Lactobacillus delbrueckii subsp. bulgaricus , suitable for use in the treatment or prevention of Helicobacter pylori infection.
- Who is the assignee on this patent?
- Garault Peggy, Quere Gaelle, Bourdet-Sicard Raphaelle, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification A61K35/747. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).