Devices and methods for determination of species including chemical warfare agents

Patent metadata

Field	Value
Publication number	US-9267908-B2
Application number	US-201514596983-A
Country	US
Kind code	B2
Filing date	Jan 14, 2015
Priority date	Mar 4, 2008
Publication date	Feb 23, 2016
Grant date	Feb 23, 2016

Abstract

The present invention generally provides devices, systems, and methods for determination of one or more analytes. The analyte may be determined by monitoring, for example, a change in an electrical, optical, or other signal of a material (e.g., sensor material) present within the device, upon exposure to the analyte. The signal may be an electrical and/or optical property of the device. In some cases, devices described herein may be useful as sensors for the determination of analytes such as explosives, chemical warfare agents, and/or toxins.

First claim

What is claimed:

1. A device for determining an analyte, comprising:
a first electrode and a second electrode,
a sensor material in electrochemical communication with the first and the second electrodes, wherein resistance to current flow between the first and second electrode is affected by the sensor material;
wherein the sensor material comprises a plurality of carbon nanotubes and a polymer material integrally connected to at least a portion of the plurality of carbon nanotubes, such that the carbon nanotubes are substantially contained within the polymer material;
wherein the sensor material comprises a binding site, the binding site comprising a transition metal complex; and
wherein the analyte, if present, interacts with the sensor material to affect resistance to current flow between the first and second electrodes, thereby generating a signal in the device by which the analyte is determined.

2. A device as in claim 1 , wherein the analyte comprises an olefin.

3. A device as in claim 1 , wherein the analyte comprises nitric oxide.

4. A device as in claim 1 , wherein the analyte comprises a thiol or thioether.

5. A device as in claim 1 , wherein the analyte comprises an amine.

6. A device as in claim 1 , wherein the analyte is an organic compound.

7. A device as in claim 1 , wherein at least two analytes are present in the sample.

8. A device as in claim 7 , wherein the at least two analytes, if present, interact with the sensor material to affect resistance to current flow between the first and second electrodes.

9. A method as in claim 1 , wherein the transition metal complex comprises palladium.

10. A method as in claim 1 , wherein the transition metal complex is PdCl 2 (ethylene)(pyridine).

Assignees

• Massachusetts Inst Technology

Inventors

• Wang Fei
• Swager Timothy M

Classifications

• B82Y15/00 Primary

  Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors · CPC title

• G01N27/126

  comprising organic polymers · CPC title

• G01N27/127 Primary

  comprising nanoparticles · CPC title

• Y10S977/742

  Carbon nanotubes, CNTs · CPC title

• Y10S977/957

  Of chemical property or presence · CPC title