Eye mounted device for therapeutic agent release
US-12167978-B2 · Dec 17, 2024 · US
US9259472B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9259472-B2 |
| Application number | US-201414180396-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 14, 2014 |
| Priority date | Apr 26, 2008 |
| Publication date | Feb 16, 2016 |
| Grant date | Feb 16, 2016 |
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The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that interferes with the cross-linking of galactomannan and borate. Optionally, the formulations are substantially free of divalent cations.
Opening claim text (preview).
What is claimed is: 1. An ophthalmic formulation comprising a galactomannan, borate, and a cis-diol, wherein said formulation is substantially free of divalent cations, wherein said galactomannan is present at a concentration of about 0.1 w/v % to about 2.0 w/v % and said borate is present at a concentration of about 0.2 w/v % to about 2.0 w/v % and said cis-diol is sorbitol at a concentration of 0.5 to 5.0 w/v %, said formulation further comprising one or more pharmaceutically ac…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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