Auxin biosynthesis inhibitor

Patent metadata

Field	Value
Publication number	US-9259000-B2
Application number	US-201213261726-A
Country	US
Kind code	B2
Filing date	Feb 28, 2012
Priority date	Feb 28, 2011
Publication date	Feb 16, 2016
Grant date	Feb 16, 2016

Abstract

An object of the present invention is to provide an auxin biosynthesis inhibitor superior to L-AOPP. The object can be attained by a compound represented by general formula (I): wherein, R 1 to R 5 and X are the same as defined in the specification or a salt or solvate thereof.

First claim

The invention claimed is:

1. A compound represented by general formula (I):

wherein
R 1 is chlorophenyl, bromophenyl, biphenyl, phenoxyphenyl, 4-chloro-3-methylphenyl, 4-chloro-2-methylphenyl, dichlorophenyl, 6-methoxy-2-naphthyl, naphthyl or quinolinyl;
R 2 is a C 1-6 alkyl group;
R 3 and R 4 are each hydrogen, or R 3 is hydrogen and R 4 is acetyl or benzoyl, or R 3 and R 4 together form propan-2-ylidene or R 3 and R 4 , together with a nitrogen atom to which R 3 and R 4 are bound, form phthalimide or succinimide;
R 5 is hydrogen; and
X is O,
or a salt or solvate thereof.

2. The compound according to claim 1 , wherein
R 1 is 2-naphthyl, R 2 is methyl, R 3 and R 4 are each hydrogen or R 3 and R 4 , together with a nitrogen atom to which R 3 and R 4 are bound, form phthalimide, R 5 is hydrogen, and X is O.

3. A method for inhibiting biosynthesis of auxin in a plant, comprising applying the compound according to claim 1 to the plant.

4. A method for inhibiting tryptophan aminotransferase in a plant, comprising applying the compound according to claim 1 to the plant.

5. A method for inhibiting tryptophan aminotransferase, comprising bringing the compound according to claim 1 into contact with the tryptophan aminotransferase in vitro.

6. A method for regulating growth of a plant, comprising applying the compound according to claim 1 to the plant.

7. A method for weeding a plant, comprising applying the compound according to claim 1 to the plant.

Assignees

• Shimada Yukihisa
• Kikuzato Ko
• Narukawa Megumi
• Asami Tadao
• Soeno Kazuo
• Riken
• Public Univ Corp Yokohama City

Inventors

• Shimada Yukihisa
• Kikuzato Ko
• Narukawa Megumi
• Asami Tadao
• Soeno Kazuo

Classifications

• C07C239/20

  having oxygen atoms of hydroxylamino groups etherified · CPC title

• C07D207/46

  with hetero atoms directly attached to the ring nitrogen atom · CPC title

• C07C259/06

  having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms · CPC title

• A01N43/42

  condensed with carbocyclic rings · CPC title

• A01N43/38

  condensed with carbocyclic rings · CPC title