Neisserial antigenic peptides
US-9067987-B2 · Jun 30, 2015 · US
Neisseria meningitidis antigens and compositions
US9249196B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9249196-B2 |
| Application number | US-201213359442-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 26, 2012 |
| Priority date | May 1, 1998 |
| Publication date | Feb 2, 2016 |
| Grant date | Feb 2, 2016 |
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- Title
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- Abstract
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Abstract
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The invention provides proteins from Neisseria meningitidis , including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
First claim
Opening claim text (preview).
We claim: 1. A composition comprising an immunostimulatory effective amount of aluminum salt adjuvant and a purified polypeptide comprising a fragment of the amino acid sequence of SEQ ID NO: 2536, wherein the fragment comprises 18 or more consecutive amino acids from the amino acid sequence, and wherein the purified polypeptide is immunogenic. 2. The composition of claim 1 comprising the fragment, wherein the fragment comprises 20 or more consecutive amino acids from the amino acid sequence of SEQ ID NO: 2536. 3. The composition of claim 1 , in combination with a pharmaceutically acceptable carrier. 4. The composition of claim 2 , in combination with a pharmaceutically acceptable carrier. 5. The composition of claim 1 , in further combination with a pH buffering agent. 6. The composition of claim 2 , in further combination with a pH buffering agent. 7. The composition of claim 1 , wherein the composition is formulated as an injectable. 8. The composition of claim 1 , wherein the purified polypeptide is recombinant. 9. The composition of claim 1 , wherein the aluminum salt adjuvant comprises an aluminum hydroxide adjuvant. 10. The composition of claim 1 , wherein the aluminum salt adjuvant comprises an aluminum phosphate adjuvant.
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Inventors
Classifications
Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00) · CPC title
- C07K14/22Primary
from Neisseriaceae (F) · CPC title
Inorganic adjuvants · CPC title
Immunomodulators · CPC title
Antigenic peptides or proteins · CPC title
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Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9249196B2 cover?
- The invention provides proteins from Neisseria meningitidis , including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
- Who is the assignee on this patent?
- Fraser Claire, Galeotti Cesira, Grandi Guido, and 12 more
- What technology area does this patent fall under?
- Primary CPC classification C07K14/22. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 6 related publications on this page (citations in our corpus or others sharing the same primary CPC).