Anti-microbial implant

Patent metadata

Field	Value
Publication number	US-9247973-B2
Application number	US-86354707-A
Country	US
Kind code	B2
Filing date	Sep 28, 2007
Priority date	Sep 28, 2007
Publication date	Feb 2, 2016
Grant date	Feb 2, 2016

Abstract

Non-load-bearing, drug-eluting components that can be added to load bearing spinal implants.

First claim

We claim:

1. An assembly comprising i) a bone screw comprising a head having a contour and a shaft extending from the head, and ii) a non-load bearing, resorbable bone screw cap loaded with a pharmaceutical compound, wherein the cap fits substantially closely to the contour of the head,
wherein the cap is non-load bearing when attached to the bone screw head in its final position when the assembly is fully implanted onto bone;
wherein the bone screw is a polyaxial pedicle screw.

2. The assembly of claim 1 wherein the cap comprises:
a) a cover having a perimeter and a center.

3. The assembly of claim 2 wherein the cap further comprises:
b) a shank extending downward from the cover.

4. The assembly of claim 3 wherein the cover and shank fit substantially closely to an outer contour of the head of the bone screw.

5. The assembly of claim 3 wherein the cover and shank fit substantially closely to an inner contour of the head of the bone screw.

6. The assembly of claim 3 wherein the cap further comprises:
c) means for connecting the cap to the bone screw.

7. The assembly of claim 6 wherein the means comprises a flange.

8. The assembly of claim 7 wherein the flange extends from the shank and engages a recess in the contour of the bone screw.

9. The assembly of claim 7 wherein the flange extends inward from the shank.

10. The assembly of claim 7 wherein the flange extends from the center of the cover and engages a recess in the head of the bone screw.

11. The assembly of claim 6 wherein the means comprises a recess.

12. The assembly of claim 11 wherein the recess extends into the perimeter of the cover and engages a flange in the contour of the bone screw.

13. The assembly of claim 6 wherein the means comprises an adhesive or a curing composition.

14. The assembly of claim 6 wherein the means comprises a snap-on connection.

15. The assembly of claim 3 wherein the cover substantially defines a circle and the shank substantially defines an annulus.

16. The assembly of claim 3 wherein the cover and shank substantially define a hollow hemisphere.

17. The assembly of claim 3 wherein the shank extends downward from the perimeter of the cover.

18. The assembly of claim 3 wherein the shank extends downward from the center of the cover.

19. The assembly of claim 3 wherein the cover and shank are modular.

20. The assembly of claim 1 further comprising an extension.

21. The assembly of claim 1 wherein the pharmaceutical compound is an anti-microbial compound.

22. The assembly of claim 1 wherein the pharmaceutical compound is present as a coating.

23. The assembly of claim 1 wherein the pharmaceutical compound is embedded with the cap.

24. A spinal screw assembly, comprising:
a) a bone screw comprising a head and a shaft extending from the head,
b) a non-load bearing resorbable spinal component comprising a pharmaceutical compound,
wherein the non-load bearing spinal component is attached to the head of the bone screw,
wherein the spinal component is non-load bearing when attached to the bone screw head in its final position when the assembly is fully implanted onto bone;
wherein the bone screw is a polyaxial pedicle screw,
wherein the non-load bearing spinal component is a snap-on type having features that mate with corresponding mating features provided on the pedicle screw.

Assignees

• Fisher Michael Alan
• Serhan Hassan
• Haw Kins John Riley
• Slivka Michael Andres
• Depuy Synthes Products Inc

Inventors

• Fisher Michael Alan
• Serhan Hassan
• Haw Kins John Riley
• Slivka Michael Andres

Classifications

• A61B17/8605

  Heads, i.e. proximal ends projecting from bone · CPC title

• A61M31/002

  Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time (artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50) · CPC title

• A61B17/7002

  Longitudinal elements, e.g. rods · CPC title

• A61B17/7032

  Screws or hooks with U-shaped head or back through which longitudinal rods pass · CPC title

• A61B2017/561

  Implants with special means for releasing a drug · CPC title