Robotic Microtool Control in an Intelligent Automated In Vitro Fertilization and Intracytoplasmic Sperm Injection Platform
US-2024426856-A1 · Dec 26, 2024 · US
US9230323B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9230323-B2 |
| Application number | US-201514714811-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 18, 2015 |
| Priority date | May 19, 2014 |
| Publication date | Jan 5, 2016 |
| Grant date | Jan 5, 2016 |
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According to one embodiment, an X-ray diagnostic apparatus includes processing circuitry. The processing circuitry generates a plurality of contrast images sequentially based on X-rays after administration of a contrast medium to the object, determines a monitoring region in the plurality of contrast images, monitors change in signal strength of each of pixels included in the monitoring region, and determines whether or not the signal strength of each of the pixels included in the monitoring region satisfies a specified condition. The processing circuitry controls an X-ray generator based on a result of the determination so as to reduce an X-ray dose or turn off irradiation. The processing circuitry generates a parametric image based on a feature amount determined by change in signal strength of each of pixels of a part of the plurality of contrast images sequentially generated before the X-ray generator is controlled based on the result of the determination.
Opening claim text (preview).
The invention claimed is: 1. An X-ray diagnostic apparatus, comprising: an X-ray generator configured to generate X-rays for irradiating an object; and processing circuitry configured to generate a plurality of contrast images sequentially based on the X-rays after administration of a contrast medium to the object, determine a monitoring region in the plurality of contrast images, monitor change in signal strength of each of pixels included in the monitoring region of the plurality of contrast images sequentially generated, determine whether or not the signal strength of each of the pixels included in the monitoring region satisfies a specified condition, control the X-ray generator based on a result of the determination so as to reduce an X-ray dose or to turn off irradiation of the X-rays, and generate a parametric image based on a feature amount determined by change in signal strength of each of pixels of a part of the plurality of contrast images sequentially generated, the part of the plurality of contrast images sequentially generated being generated before the X-ray generator is controlled based on the result of the determination. 2. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry sequentially generates a plurality of difference images between each of the plurality of contrast images sequentially generated and a mask image generated before the administration of the contrast medium to the object, and generates the parametric image based on the feature amount determined by change in signal strength of each of pixels of a part of the plurality of difference images sequentially generated, the part of the plurality of difference images sequentially generated being generated before the X-ray generator is controlled based on the result of the determination. 3. The X-ray diagnostic apparatus according to claim 1 , wherein the feature amount is time at which a peak in the change in signal strength appears. 4. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry determines a plurality of monitoring regions. 5. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry determines whether or not the signal strength of each of the pixels included in the monitoring region is lowered by a specified percentage from a peak. 6. The X-ray diagnostic apparatus according to claim 1 , further comprising a display to display the image generated by the processing circuitry, wherein the processing circuitry determines, as the monitoring region, a region selected from the image displayed on the display as related to treatment of the object. 7. The X-ray diagnostic apparatus according to claim 1 , wherein the monitoring region is specified on the image generated by the processing circuitry such that the monitoring region has a prescribed range and encircled with a closed curve in a rectangular, circular, or oval shape. 8. The X-ray diagnostic apparatus according to claim 1 , wherein the monitoring region is specified on the image generated by the processing circuitry such that the monitoring region has a belt-like region expressed with a curved line or a straight line having a prescribed width. 9. The X-ray diagnostic apparatus according to claim 1 , wherein the monitoring region is specified on the image generated by the processing circuitry such that the monitoring region has a prescribed range corresponding to a point specified on a blood vessel included in the image generated by the processing circuitry. 10. The X-ray diagnostic apparatus according to claim 1 , wherein the monitoring region is specified on the image generated by the processing circuitry such that the monitoring region is on a blood vessel in a prescribed distance from a treatment target portion on the image generated by the processing circuitry. 11. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry sets all the pixels included in the monitoring region as monitoring targets, monitors successive change in signal strength of each of pixels set as the monitoring targets in real time, and determines whether or not the specified condition is satisfied in all pixels set as the monitoring targets. 12. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry sets a plurality of pixels, selected out of pixels included in the monitoring region, as monitoring targets, monitors successive change in signal strength of each of pixels set as the monitoring targets in real time, and determines whether or not the specified condition is satisfied in all pixels set as the monitoring targets. 13. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry determines, based on the feature amount, whether or not the condition is satisfied in all pixels set as monitoring targets. 14. The X-ray diagnostic apparatus according to claim 13 , wherein the feature amount is at least one of: a maximum concentration value at time to peak (TP) when a concentration of the contrast medium is a maximum in a time density curve representative of successive change in the concentration based on the signal strength; and a half-width concentration value that is a half width value of the time density curve, and the processing circuitry determines that the condition is satisfied when the concentration is lowered by a specified percentage from the maximum concentration value or from the half-width concentration value. 15. The X-ray diagnostic apparatus according to claim 14 , wherein the processing circuitry calculates at least one feature amount out of: the maximum concentration value; the half-width concentration value; mean transit time of the contrast medium, a lower area of the time density curve, a blood flow velocity of the object obtained from the time density curve, a blood flow rate of the object obtained from the time density curve, arrival time of the contrast medium at each of the pixels based on the time density curve, the TP, and a gradient to the maximum concentration value in the time density curve, and the processing circuitry selects any one of the feature amounts, and determines whether or not the specified condition is satisfied based on whether or not a condition for calculating the selected feature amount is satisfied. 16. The X-ray diagnostic apparatus according to claim 15 , wherein the processing circuitry generates, as the parametric image, a color image such that a color corresponding to values of the feature amount are allocated to each pixel of the color image. 17. The X-ray diagnostic apparatus according to claim 2 , wherein the processing circuitry generates the plurality of difference images as a plurality of first difference images, and then sequentially generates a plurality of second difference images based on the X-rays, determines the monitoring region in the plurality of second difference images based on the plurality of first difference images, determines whether or not signal strength of each of pixels included in the monitoring region of the plurality of second difference images satisfies the specified condition, controls the X-ray generator based on a result of the determination so as to reduce a dose of the X-rays for imaging of the plurality of second difference images or to turn off irradiation of the X-rays, and generates the parametric image based on the feature amount determined by change in signal strength of each of pixels of a part of the plurality of second difference images, the
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