Methods and devices for analyzing species to determine diseases
US-2024264160-A1 · Aug 8, 2024 · US
Method for detecting thyroid carcinoma
US9229003B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9229003-B2 |
| Application number | US-50343409-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 15, 2009 |
| Priority date | Jul 16, 2008 |
| Publication date | Jan 5, 2016 |
| Grant date | Jan 5, 2016 |
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Abstract
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It is an object of the present invention to identify a gene that exhibits behavior which is characteristic of carcinomas such as thyroid carcinoma, so as to provide a method for detecting carcinoma and a cell growth suppressing agent. The present invention provides a method for detecting carcinoma, which comprises detecting malignant transformation by detecting at least one alteration of gene existing in chromosomal regions 1q41, 3q28, 7q31.2, 8p12, 8q22.2, 8q24.21, 11q4.1, 17q12, 20q11, 9p21.3, 16q13.2, and 16q23.1 in a specimen.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for detecting an increased risk of anaplastic thyroid carcinoma in a human, which comprises: a) detecting mRNA of an itchy homolog E3 ubiquitin protein ligase (ITCH) gene in a thyroid biopsy sample from the human by performing an RT-PCR method using primers consisting of SEQ ID NO: 17 and 18 and determining an increased level of mRNA in the sample as compared with a non-anaplastic thyroid carcinoma sample from a human; b) detecting protein expression of an ITCH gene in the sample by performing an immunohistochemical method; and c) determining an increase risk of anaplastic thyroid carcinoma in the human when an increased level of mRNA and protein expression is detected.
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Classifications
for cancer (immunoassay for cancer G01N33/575) · CPC title
Polymorphic or mutational markers · CPC title
Disease subtyping, staging or classification · CPC title
Antineoplastic agents · CPC title
- G01N33/57557Primary
of other specific parts of the body, e.g. brain · CPC title
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- What does patent US9229003B2 cover?
- It is an object of the present invention to identify a gene that exhibits behavior which is characteristic of carcinomas such as thyroid carcinoma, so as to provide a method for detecting carcinoma and a cell growth suppressing agent. The present invention provides a method for detecting carcinoma, which comprises detecting malignant transformation by detecting at least one alteration of gene e…
- Who is the assignee on this patent?
- Inazawa Johji, Imoto Issei, Ishihara Takaya, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification G01N33/57557. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).