Triggered molecular geometry based bioimaging probes
US-8962241-B2 · Feb 24, 2015 · US
US9217151B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9217151-B2 |
| Application number | US-15289308-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 16, 2008 |
| Priority date | May 16, 2007 |
| Publication date | Dec 22, 2015 |
| Grant date | Dec 22, 2015 |
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The present invention relates generally to programming of biomolecular self-assembly pathways and related methods and constructs. A versatile nucleic acid hairpin motif for programming biomolecular self-assembly pathways for a wide variety of dynamic functions, reaction graphs for specifying pathways, and methods of using the hairpin motif are provided.
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What is claimed is: 1. A system for performing a dynamic function comprising: a first hairpin monomer comprising: a first domain comprising a first toehold and a first propagation region, wherein the first toehold is exposed such that it is available to hybridize to a portion of a first nucleic acid sequence complementary to the first domain, and wherein the first toehold is located at an end of the monomer; and a second domain comprising a second toehold and a second propagat…
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