Epoxy chemistry derived materials as reversed-phase and hydrophobic interaction chromatography media, method for their synthesis and use

Patent metadata

Field	Value
Publication number	US-9216403-B2
Application number	US-201313841484-A
Country	US
Kind code	B2
Filing date	Mar 15, 2013
Priority date	Mar 15, 2013
Publication date	Dec 22, 2015
Grant date	Dec 22, 2015

Abstract

This invention provides aqueous-compatible, polar-embedded reversed-phase stationary phase compositions, devices and systems comprising the stationary phases as well as methods of producing these compositions using epoxide ring-opening reactions. Also provided are methods of using the stationary phases of the invention in separations.

First claim

What is claimed is:

1. A composition comprising a ligand covalently bound to a substrate, said ligand having a structure according to Formula (I)

wherein
n is an integer selected from 0 and 1;
X 1 is O or S;
X 2 is O or S,
with the proviso that at least one of X 1 or X 2 is O;
R 20 is selected from the group consisting of, substituted or unsubstituted pheny…

Assignees

• Dionex Corp

Inventors

• Liu Xiaodong
• Cao Liang
• Pohl Christopher A

Classifications

• B01J20/286

  Operations & Transport · mapped topic

• G01N30/02

  Physics · mapped topic

• B01J20/3257

  Operations & Transport · mapped topic

• B01J20/287

  Operations & Transport · mapped topic

• B01J20/22 Primary

  Operations & Transport · mapped topic