Inhibitors of tyk2
US-2024425484-A1 · Dec 26, 2024 · US
US9212166B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9212166-B2 |
| Application number | US-201314373163-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 21, 2013 |
| Priority date | Jan 20, 2012 |
| Publication date | Dec 15, 2015 |
| Grant date | Dec 15, 2015 |
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The present invention provides crystalline form of intermediates of Formula 2A, The present invention also provides process for the preparation of dabigatran etexilate mesylate; polymorph of intermediates thereof; particularly processes for the preparation of crystalline form of intermediates. The present invention also relates to the use of crystalline intermediates for the preparation of dabigatran etexilate mesylate.
Opening claim text (preview).
We claim: 1. A process for preparation of dabigatran etexilate of Formula (F) or a pharmaceutically acceptable salt thereof, the process comprising the steps of: (a) treating crystalline ethyl 3-(2-((4-cyanophenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate of Formula (2B) with an acid in organic solvent to obtain a…
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