Gene therapy for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes
US-12173314-B2 · Dec 24, 2024 · US
US9211362B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9211362-B2 |
| Application number | US-201213491985-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 8, 2012 |
| Priority date | Jun 30, 2003 |
| Publication date | Dec 15, 2015 |
| Grant date | Dec 15, 2015 |
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A connective tissue scaffold including opposed first and second anchoring segments formed from a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to a longitudinal axis of the scaffold and a plurality of bioresorbable polymeric fibers oriented in a direction substantially transverse to a longitudinal axis of the scaffold. A central segment joins the first and second anchoring segments and includes a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to the longitudinal axis of the scaffold. The scaffold can also a tissue particle and/or biological component.
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What is claimed is: 1. A connective tissue scaffold, comprising: opposed first and second anchoring eyelets located at opposed ends of the scaffold along a longitudinal axis of the scaffold that extends along a longitudinal length thereof, the eyelets each being formed of a plurality of bioresorbable eyelet region polymeric fibers and defining an open area, and central axes extending through each of the open areas of the first and second anchoring eyelets such that the central axe…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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