Syringe-Based Microbubble Generator
US-2024226418-A1 · Jul 11, 2024 · US
US9211348B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9211348-B2 |
| Application number | US-201113814329-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 9, 2011 |
| Priority date | Aug 9, 2010 |
| Publication date | Dec 15, 2015 |
| Grant date | Dec 15, 2015 |
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Gas-filled microvesicles associated with a polypeptide comprising a sequence of amino acids, said sequence exhibiting binding affinity for selectins, particularly p-selectin. The gas-filled microvesicles can be used in ultrasound imaging.
Opening claim text (preview).
The invention claimed is: 1. An aqueous suspension comprising a gas-filled microvesicle, said microvesicle comprising a targeting construct comprising: a) an amphiphilic compound; and b) a homodimeric polypeptide consisting of two polypeptide monomers, wherein each polypeptide monomer consists of at most 200 amino acid residues, comprises a single lysine amino acid residue, at least amino acids 5-16 as set forth in SEQ ID NO:1 and at least one cysteine residue; wherein the pep…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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