Method and device for immunoassay using nucleotide conjugates

US9207246B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9207246-B2
Application numberUS-201313865425-A
CountryUS
Kind codeB2
Filing dateApr 18, 2013
Priority dateDec 31, 2008
Publication dateDec 8, 2015
Grant dateDec 8, 2015

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Abstract

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A composition of matter for use in an immunoassay devices and method comprising a signal antibody, e.g., FAB fragment, covalently linked to a first nucleotide; and one or more signal elements, e.g., signal enzymes such as ALP or fluorescent dyes, each covalently linked to a second nucleotide, wherein the first nucleotide has one or more repeated sequences, and the second nucleotide is bound to one of the one or more repeated sequences on said first nucleotide, and wherein the ratio of the signal antibody to the signal element is controlled by the number of repeated sequences.

First claim

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What is claimed is: 1. A single-use cartridge for performing an immunoassay, comprising: a sample entry port for receiving a blood sample suspected of containing a target analyte, a conduit containing an electrode, a region containing a wash fluid, a waste chamber, immobilized first antibody capable of binding to said target analyte, second antibody disposed in a solubilizing agent disposed within said conduit and capable of binding to said target analyte, wherein the s…

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What does patent US9207246B2 cover?
A composition of matter for use in an immunoassay devices and method comprising a signal antibody, e.g., FAB fragment, covalently linked to a first nucleotide; and one or more signal elements, e.g., signal enzymes such as ALP or fluorescent dyes, each covalently linked to a second nucleotide, wherein the first nucleotide has one or more repeated sequences, and the second nucleotide is bound to …
Who is the assignee on this patent?
Abbott Point Of Care Inc
What technology area does this patent fall under?
Primary CPC classification G01N33/6887. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Dec 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).