Needle array assembly and method for delivering therapeutic agents

US9205201B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9205201-B2
Application numberUS-201414178045-A
CountryUS
Kind codeB2
Filing dateFeb 11, 2014
Priority dateAug 14, 2007
Publication dateDec 8, 2015
Grant dateDec 8, 2015

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  2. Abstract

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  5. First independent claim

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Abstract

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A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment.

First claim

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The invention claimed is: 1. A device for delivery of one or more agents into a tumor, comprising: two or more needles arranged in an array configured to deliver said one or more agents, wherein at least one of said one or more agents is a chemotherapy agent, into said tumor, wherein a first region of permeation of said one or more agents in said tumor is separate from a second region of permeation of said one or more agents in said tumor, and wherein a first agent is delivered thr…

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What does patent US9205201B2 cover?
A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupl…
Who is the assignee on this patent?
Hutchinson Fred Cancer Res
What technology area does this patent fall under?
Primary CPC classification A61M5/3298. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Dec 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).