Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis

US9205136B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9205136-B2
Application numberUS-201414152544-A
CountryUS
Kind codeB2
Filing dateJan 10, 2014
Priority dateMar 31, 2000
Publication dateDec 8, 2015
Grant dateDec 8, 2015

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Abstract

Official abstract text for this publication.

Methods of enhancing angiogenesis utilizing carboxy-terminal truncated human tyrosyl-tRNA synthetase (TyrRS) are disclosed. The truncated human TyrRS polypeptides comprise residues 1-364 or residues 1-343 of full length human TyrRS (SEQ ID NO: 2).

First claim

Opening claim text (preview).

We claim: 1. A method for enhancing angiogenesis in a mammal to achieve a therapeutic effect; the method comprising the step of administering to the mammal an effective amount of a polypeptide which consists essentially of residues 1 to 364 of SEQ ID NO:2 or a dimer thereof encoded by a nucleic acid comprising a coding region consisting of a nucleotide sequence at least 95% identical to a sequence selected from the group consisting of: (a) a polynucleotide encoding a polypeptide…

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Inventors

Classifications

  • A61K38/53Primary

    Human Necessities · mapped topic

  • Human Necessities · mapped topic

  • C07H21/04Primary

    Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

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What does patent US9205136B2 cover?
Methods of enhancing angiogenesis utilizing carboxy-terminal truncated human tyrosyl-tRNA synthetase (TyrRS) are disclosed. The truncated human TyrRS polypeptides comprise residues 1-364 or residues 1-343 of full length human TyrRS (SEQ ID NO: 2).
Who is the assignee on this patent?
Scripps Research Inst
What technology area does this patent fall under?
Primary CPC classification A61K38/53. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Dec 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).