Compositions and methods comprising erythrohydroxybupropion and related compounds for improving the efficacy of dextromethorphan

US9205083B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9205083-B2
Application numberUS-201414554988-A
CountryUS
Kind codeB2
Filing dateNov 26, 2014
Priority dateNov 5, 2013
Publication dateDec 8, 2015
Grant dateDec 8, 2015

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  2. Abstract

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Abstract

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This disclosure relates to methods of improving the efficacy of dextromethorphan, or providing beneficial pharmacokinetic effects to dextromethorphan, comprising co-administering erythrohydroxybupropion, or a prodrug thereof, and dextromethorphan to a human being. Dosage forms, drug delivery systems, and methods related to dextromethorphan and erythrohydroxybupropion or a prodrug of erythrohydroxybupropion are also disclosed.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of increasing the metabolic lifetime of dextromethorphan, comprising co-administering erythrohydroxybupropion or bupropion with dextromethorphan to a human being once or twice a day for at least eight consecutive days, wherein erythrohydroxybupropion or bupropion is administered in an amount that results in an AUC 0-12 of erythrohydroxybupropion in the human being, on day 8, that is at least about 200 ng·hr/mL, wherein the human being is an e…

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What does patent US9205083B2 cover?
This disclosure relates to methods of improving the efficacy of dextromethorphan, or providing beneficial pharmacokinetic effects to dextromethorphan, comprising co-administering erythrohydroxybupropion, or a prodrug thereof, and dextromethorphan to a human being. Dosage forms, drug delivery systems, and methods related to dextromethorphan and erythrohydroxybupropion or a prodrug of erythrohydr…
Who is the assignee on this patent?
Antecip Bioventures Ii Llc
What technology area does this patent fall under?
Primary CPC classification A61K31/485. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Dec 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).