Solid pharmaceutical tablet
US-2024226038-A9 · Jul 11, 2024 · US
US9205083B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9205083-B2 |
| Application number | US-201414554988-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 26, 2014 |
| Priority date | Nov 5, 2013 |
| Publication date | Dec 8, 2015 |
| Grant date | Dec 8, 2015 |
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This disclosure relates to methods of improving the efficacy of dextromethorphan, or providing beneficial pharmacokinetic effects to dextromethorphan, comprising co-administering erythrohydroxybupropion, or a prodrug thereof, and dextromethorphan to a human being. Dosage forms, drug delivery systems, and methods related to dextromethorphan and erythrohydroxybupropion or a prodrug of erythrohydroxybupropion are also disclosed.
Opening claim text (preview).
The invention claimed is: 1. A method of increasing the metabolic lifetime of dextromethorphan, comprising co-administering erythrohydroxybupropion or bupropion with dextromethorphan to a human being once or twice a day for at least eight consecutive days, wherein erythrohydroxybupropion or bupropion is administered in an amount that results in an AUC 0-12 of erythrohydroxybupropion in the human being, on day 8, that is at least about 200 ng·hr/mL, wherein the human being is an e…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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