Systems for and methods of facilitating focusing an optical scanner

Patent metadata

Field	Value
Publication number	US-9201230-B2
Application number	US-201414491708-A
Country	US
Kind code	B2
Filing date	Sep 19, 2014
Priority date	Mar 18, 2005
Publication date	Dec 1, 2015
Grant date	Dec 1, 2015

Abstract

Systems and methods for facilitating focusing of an image scanner, such as a confocal microscope, are disclosed. Measurement of optical characteristics in certain areas of a test sample are compared to stored or baseline optical characteristic profiles to determine an appropriate correction to properly focus the scanner. In one aspect, the method includes obtaining a dynamic profile at a current detection region of a test sample and associating the dynamic profile to a profile selected from a set of stored baseline profiles. Each of the stored baseline profiles is associated with a correction.

First claim

The invention claimed is:

1. A method, comprising:
providing a library of reference profiles, wherein each reference profile includes values for at least one parameter for at least two points of a scanline;
directing excitation radiation from an optical scanning system across one dimension of a two-dimensional scan area of a test sample;
obtaining a dynamic profile including at least two points of a scanline of the test sample by detecting radiation emanating from the one dime…

Assignees

• Illumina Inc

Inventors

• Feng Wenyi

Classifications

• G02B21/008

  Physics · mapped topic

• G02B21/006 Primary

  Physics · mapped topic

• G01N2015/1452

  Physics · mapped topic