Methods of treating cancer by targeting tumor-associated macrophages
US-2024415921-A1 · Dec 19, 2024 · US
US9201014B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9201014-B2 |
| Application number | US-201213625832-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 24, 2012 |
| Priority date | Mar 24, 2010 |
| Publication date | Dec 1, 2015 |
| Grant date | Dec 1, 2015 |
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A compound of structural formula (I): The values and alternative values are as defined herein. The invention also includes biosensors comprising nanoparticles functionalized with a compound of structural formula (I). Also described is a method for labeling a biomolecule using a compound of structural formula (I) and a method of detecting a target biomolecule using a compound of structural formula (I) or a biosensor of the invention.
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What is claimed is: 1. A compound represented by the following structural formula: wherein X is iodo. 2. A method of detecting activated macrophage cells in an animal, comprising: a) administering to the animal the compound of claim 1 in an amount sufficient to stain the activated macrophage cells; and b) visualizing the stained activated macroph…
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