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Diagnostic methods and kit for detecting cancer
US9200325B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9200325-B2 |
| Application number | US-201213433722-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 29, 2012 |
| Priority date | Apr 1, 2011 |
| Publication date | Dec 1, 2015 |
| Grant date | Dec 1, 2015 |
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Abstract
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The present disclosure is directed to compositions and methods for detecting elevated microRNA U6 concentrations in serum relative to a standard microRNA (e.g. SNORD44) as a diagnostic indicator of metastatic disease. In one embodiment the methods of the present disclosure are used to diagnose the existence of, or assess the risk of, breast cancer in an individual.
First claim
Opening claim text (preview).
The invention claimed is: 1. A diagnostic screen for detecting and/or monitoring the progression of breast cancer, the diagnostic screen comprising the steps of: isolating a serum sample from a subject suspected of having breast cancer; isolating RNA in the serum sample; determining the concentration of SNORD44 small nuclear RNA (snRNA) in the subject's sample by amplifying the SNORD44 snRNA in the isolated RNA; determining the concentration of U6 snRNA in the subject's sam…
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Human Necessities · mapped topic
- C12Q1/6886Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9200325B2 cover?
- The present disclosure is directed to compositions and methods for detecting elevated microRNA U6 concentrations in serum relative to a standard microRNA (e.g. SNORD44) as a diagnostic indicator of metastatic disease. In one embodiment the methods of the present disclosure are used to diagnose the existence of, or assess the risk of, breast cancer in an individual.
- Who is the assignee on this patent?
- Nakshatri Harikrishna, Univ Indiana Res & Tech Corp
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6886. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Dec 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).