Intestinal mononuclear phagocytes as prognostic biomarker for crohn's disease
US-2024425923-A1 · Dec 26, 2024 · US
US9200322B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9200322-B2 |
| Application number | US-201113580571-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 22, 2011 |
| Priority date | Feb 23, 2010 |
| Publication date | Dec 1, 2015 |
| Grant date | Dec 1, 2015 |
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The present invention provides methods and compositions for the diagnosis of acute ischemic stroke. The invention further provides methods and compositions for distinguishing acute ischemic stroke from other forms of stroke and TIAs and “stroke mimic” events. Moreover, methods and compositions are provided to facilitate the treatment of acute ischemic stroke patients.
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What is claimed is: 1. A method for the diagnosis of acute ischemic stroke in a subject, comprising obtaining a biological sample from a subject; extracting total RNA from the sample; and determining expression by biomarker-specific antibody immunoassay of a panel of only 4, 5, 6, 7, 8, 9, 10, 15 or 20 individual biomarkers in the sample obtained from the subject, wherein four of said individual biomarkers are: (a) chemokine receptor 7 (CCR7); (b) chondroitin sulfate proteo…
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