Gastric reflux resistant dosage forms

US9192582B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9192582-B2
Application numberUS-201414507327-A
CountryUS
Kind codeB2
Filing dateOct 6, 2014
Priority dateDec 22, 2005
Publication dateNov 24, 2015
Grant dateNov 24, 2015

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Abstract

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Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent. Suitable gastric resistant natural polymers include polysaccharides such as pectin and pectin-like polymers. The film-forming composition can be used to prepare soft or hard shell gelatin capsules which can encapsulate a liquid or semi-solid fill material or a solid tablet (Softlet®) comprising an active agent and one or more pharmaceutically acceptable excipients. Alternatively, the composition can be administered as a liquid with an active agent dissolved or dispersed in the composition. The compositions are not only gastric resistant but may also prevent gastric reflux associated with odor causing liquids, such as fish oil or garlic oil, encapsulated in a unit dosage form and esophageal irritation due to the reflux of irritant drugs delivered orally.

First claim

Opening claim text (preview).

I claim: 1. An oral gastric resistant soft capsule shell, prepared by a process comprising: A) preparing a mixture comprising (a) pectin in an amount from 2% to less than 5% by weight; (b) gelatin in an amount from 25% to 40% by weight; (c) glycerol in an amount from 8% to 30% by weight; (d) a divalent cation selected from the group consisting of calcium salts, magnesium salts, and calcium gelatin in an amount from 1% to 2% by weight; and (e) water; B) casting the gel…

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What does patent US9192582B2 cover?
Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent. Suitable gastric resistant natural polymers include polysaccharides such as pectin and pectin-like polymers. The film-forming composition can be used to prepare soft or hard shell gelatin capsules which c…
Who is the assignee on this patent?
Banner Pharmacaps Inc, Banner Life Sciences Llc
What technology area does this patent fall under?
Primary CPC classification A61K9/4825. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Nov 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).