Tetrazole derivatives
US-2024382468-A2 · Nov 21, 2024 · US
US9192582B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9192582-B2 |
| Application number | US-201414507327-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 6, 2014 |
| Priority date | Dec 22, 2005 |
| Publication date | Nov 24, 2015 |
| Grant date | Nov 24, 2015 |
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Official abstract text for this publication.
Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent. Suitable gastric resistant natural polymers include polysaccharides such as pectin and pectin-like polymers. The film-forming composition can be used to prepare soft or hard shell gelatin capsules which can encapsulate a liquid or semi-solid fill material or a solid tablet (Softlet®) comprising an active agent and one or more pharmaceutically acceptable excipients. Alternatively, the composition can be administered as a liquid with an active agent dissolved or dispersed in the composition. The compositions are not only gastric resistant but may also prevent gastric reflux associated with odor causing liquids, such as fish oil or garlic oil, encapsulated in a unit dosage form and esophageal irritation due to the reflux of irritant drugs delivered orally.
Opening claim text (preview).
I claim: 1. An oral gastric resistant soft capsule shell, prepared by a process comprising: A) preparing a mixture comprising (a) pectin in an amount from 2% to less than 5% by weight; (b) gelatin in an amount from 25% to 40% by weight; (c) glycerol in an amount from 8% to 30% by weight; (d) a divalent cation selected from the group consisting of calcium salts, magnesium salts, and calcium gelatin in an amount from 1% to 2% by weight; and (e) water; B) casting the gel…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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