Oral care compositions containing polyorganosilsesquioxane particles

Patent metadata

Field	Value
Publication number	US-9192563-B2
Application number	US-201414249623-A
Country	US
Kind code	B2
Filing date	Apr 10, 2014
Priority date	Apr 10, 2013
Publication date	Nov 24, 2015
Grant date	Nov 24, 2015

Abstract

Oral compositions containing a polyorganosilsesquioxane particle, preferably polymethylsilsesquioxane particles having a particle size of from about 1 to about 10 microns and an orally-acceptable carrier. Method of using such compositions for the cleaning and polishing of dental enamel, such methods including the step of applying such oral care compositions to the teeth of a user.

First claim

We claim:

1. An oral composition in the form of a dentifrice, having good cleaning and stability, said composition comprising:
a) at least 0.1%, by weight of the composition, of an abrasive comprising one or more polymethylsilsesquioxane particles having an average volume weighted mean particle size of from about 1 to about 10 microns and wherein the polymethylsilsequioxane particles are spherical and smooth;
b) from about 0.01% to about 50% 0.1% to about 99.9%, by weight of the composition, of water;
c) a flavor agent;
wherein the dentifrice is in a form selected from the group consisting of gels, pastes, or combinations thereof;
wherein the dentifrice has a Pellicle Cleaning Ratio of greater than about 80; and
wherein the polymethylsilsesquioxane particles are substantially insoluble in the composition.

2. The composition of claim 1 wherein the polymethylsilsesquioxane particles have an average volume weighted mean particle size of from about 3 to about 7 microns.

3. The composition of claim 1 wherein the polymethylsilsesquioxane particles have an average volume weighted mean particle size of from about 4 to about 6 microns.

4. The composition of claim 1 wherein the composition comprises from about 0.5% to about 40%, by weight of the composition, of the polymethylsilsesquioxane particles.

5. The composition of claim 1 , wherein the composition further comprises a surfactant.

6. The composition of claim 5 , wherein the surfactant is selected from anionic surfactants and mixtures thereof.

7. The composition of claim 1 further comprising an oral care active.

8. The composition of claim 7 wherein the oral care active is selected from antibacterial agents, antiplaque agents, anticaries agents, antisensitivity agents, antierosion agents, oxidizing agents, anti-inflammatory agents, anticalculus agents, chelating agents, tooth substantive agents, antioxidants, analgesic agents, anesthetic agents, H-1 and H-2 antagonists, antiviral actives, nutrients and mixtures thereof.

9. The composition of claim 7 wherein the oral care active is selected from stannous fluoride, sodium fluoride, monofluorophosphate, essential oils, mono alkyl phosphates, hydrogen peroxide, cetylpyridinium chloride, chlorhexidine, triclosan, and combinations thereof.

10. The composition of claim 1 further comprising a secondary abrasive selected from calcium pyrophosphate, precipitated silica, fused silica, and mixtures thereof.

11. The composition of claim 1 , wherein the abrasive comprises from about 50% to about 100%, by weight of all the abrasive in the composition, of the polymethylsilsesquioxane particles.

12. The composition of claim 7 wherein the oral care active comprises a chelant.

13. The composition of claim 12 wherein the chelant is selected from polymeric organophosphate compounds including ethoxylated and non-ethoxylated mono or di alkyl phosphates or phosphonates.

14. The composition of claim 7 wherein the oral care active comprises one or more essential oils.

15. The composition of claim 1 further comprising a polymeric thickener.

16. A method of reducing plaque, gingivitis, sensitivity, oral malodor, erosion, cavities, calculus, inflammation, and staining by administering to a subject's oral cavity the composition of claim 1 .

17. An oral composition in the form of a dentifrice, having good cleaning and stability, said composition comprising:
a) at least 0.1%, by weight of the composition, of an abrasive comprising one or more polymethylsilsesquioxane particles having an average volume weighted mean particle size of from about 1 to about 10 microns and wherein the polymethylsilsequioxane particles are spherical and smooth;
b) from about 0.01% to about 50%, by weight of the composition, of water;
c) a fluoride ion source;
d) a flavor agent;
wherein the dentifrice is in a form selected from the group consisting of gels, pastes, or combinations thereof; and
wherein the dentifrice has a Pellicle Cleaning Ratio of greater than about 80.

Assignees

• Procter & Gamble

Inventors

• Midha Sanjeev
• Leblanc Michael Jude

Classifications

• A61K8/891 Primary

  saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone · CPC title

• A61K8/042

  Gels · CPC title

• A61K8/025

  Explicitly spheroidal or spherical shape · CPC title

• A61K2800/28

  Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants · CPC title

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title