Strains for the production of flavonoids from glucose

US9181539B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9181539-B2
Application numberUS-201113101462-A
CountryUS
Kind codeB2
Filing dateMay 5, 2011
Priority dateMay 7, 2010
Publication dateNov 10, 2015
Grant dateNov 10, 2015

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The invention relates to the production of flavonoids and flavonoid precursors in cells through recombinant expression of tyrosine ammonia lyase (TAL), 4-coumarate:CoA ligase (4CL), chalcone synthase (CHS), and chalcone isomerase (CHI).

First claim

Opening claim text (preview).

We claim: 1. An isolated cell that recombinantly expresses genes encoding tyrosine ammonia lyase (TAL), 4-coumarate:CoA ligase (4CL), chalcone synthase (CHS), and chalcone isomerase (CHI), and wherein the cell produces one or more flavonoids or naringenin from glucose without additional precursor supplementation, and wherein the expression of the genes encoding TAL, 4CL, CHS and CHI is balanced in the cell by constitutive expression of CHS and CHI. 2. The isolat…

Assignees

Inventors

Classifications

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • C12N9/88Primary

    Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

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Frequently asked questions

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What does patent US9181539B2 cover?
The invention relates to the production of flavonoids and flavonoid precursors in cells through recombinant expression of tyrosine ammonia lyase (TAL), 4-coumarate:CoA ligase (4CL), chalcone synthase (CHS), and chalcone isomerase (CHI).
Who is the assignee on this patent?
Stephanopoulos Gregory, Santos Christine, Koffas Mattheos, and 2 more
What technology area does this patent fall under?
Primary CPC classification C12N9/88. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Nov 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).