HDAC6 inhibitors and their uses
US-10106540-B2 · Oct 23, 2018 · US
Substituted berbines and their synthesis
US9181237B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9181237-B2 |
| Application number | US-201414504906-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 2, 2014 |
| Priority date | Oct 4, 2013 |
| Publication date | Nov 10, 2015 |
| Grant date | Nov 10, 2015 |
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Abstract
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The present invention provides substituted berbines, processes for the synthesis of substituted berbine compounds, as well as intermediates used in the synthesis of substituted berbine compounds. Also provided are methods for using the substituted berbines to inhibit cancer cell growth.
First claim
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What is claimed is: 1. A compound of Formula (V-1): wherein: R 1 R 2 , R 3 , and R 4 independently are hydrogen, halogen, OR 15 , NR 15 N 16 , nitro, cyano, thiol, hydrocarbyl, substituted hydrocarbyl, or together R 2 and R 3 along with the ring carbons to which they are attached form a ring comprising {—}O(CH 2 ) n O{—}; R 5 , R 6 , R 7 , and R 8 independently ar…
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- C07D455/03Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US9181237B2 cover?
- The present invention provides substituted berbines, processes for the synthesis of substituted berbine compounds, as well as intermediates used in the synthesis of substituted berbine compounds. Also provided are methods for using the substituted berbines to inhibit cancer cell growth.
- Who is the assignee on this patent?
- Mallinckrodt Llc
- What technology area does this patent fall under?
- Primary CPC classification C07D455/03. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Nov 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).