Molecules that bind to cd94/nkg2a heterodimer polypeptides
US-2024415889-A1 · Dec 19, 2024 · US
US9175083B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9175083-B2 |
| Application number | US-87337207-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 16, 2007 |
| Priority date | Jun 18, 2004 |
| Publication date | Nov 3, 2015 |
| Grant date | Nov 3, 2015 |
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Novel antigen-binding polypeptides (ABP) and uses thereof are provided.
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What is claimed is: 1. A method of making a bispecific antigen-binding polypeptide (ABP) comprising a sequence selected from SEQ ID NO: 19, 21, 23, 24, 26, 28, 30, 31, and comprising a ribosomally incorporated non-naturally encoded amino acid substitution, wherein the bispecific ABP is directed against a tumor cell antigen and a cytotoxic trigger molecule and the bispecific antigen-binding polypeptide is linked to a linker, polymer, or biologically active molecule, wherein the met…
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