Bacteriophage and methods of making and using
US-2016369245-A1 · Dec 22, 2016 · US
Endolysin OBPgpLYS
US9169472B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9169472-B2 |
| Application number | US-201414475900-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 3, 2014 |
| Priority date | Aug 24, 2009 |
| Publication date | Oct 27, 2015 |
| Grant date | Oct 27, 2015 |
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Abstract
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The present invention relates to a polypeptide with an amino acid sequence according to SEQ ID NO: 1 and fragments or derivatives thereof. The present invention further relates to fusion proteins comprising said polypeptide and an additional peptide stretch fused to said polypeptide at the N- or C-terminus. Moreover, the present invention relates to nucleic acid molecules encoding said polypeptide or fusion protein, vectors comprising said nucleic acid molecules and host cells comprising either said nucleic acid molecules or said vectors. In addition, the present invention relates to said polypeptide or fusion protein for use as a medicament, in particular for the treatment or prevention of Gram-negative bacterial infections, as diagnostic means, as cosmetic substance or as sanitizing agent. The present invention also relates to the use of said polypeptide or fusion protein for the treatment or prevention of Gram-negative bacterial contamination of foodstuff, of food processing equipment, of food processing plants, of surfaces coming into contact with foodstuff, of medical devices, of surfaces in hospitals and surgeries. Furthermore, the present invention relates to a pharmaceutical composition comprising said polypeptide or fusion protein.
First claim
Opening claim text (preview).
The invention claimed is: 1. A vector comprising a polynucleotide encoding a polypeptide and a nucleic acid that is heterologous to the polynucleotide, wherein the polypeptide comprises the amino acid sequence of SEQ ID NO: 1, or a fragment thereof, wherein the fragment comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 4 and 5, or comprises the amino acid sequences of SEQ ID NO: 4 and 5. 2. An isolated host cell comprising the vec…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C12N9/2462Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US9169472B2 cover?
- The present invention relates to a polypeptide with an amino acid sequence according to SEQ ID NO: 1 and fragments or derivatives thereof. The present invention further relates to fusion proteins comprising said polypeptide and an additional peptide stretch fused to said polypeptide at the N- or C-terminus. Moreover, the present invention relates to nucleic acid molecules encoding said polypept…
- Who is the assignee on this patent?
- Lysando Ag, Univ Leuven Kath
- What technology area does this patent fall under?
- Primary CPC classification C12N9/2462. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).