Compositions, methods, and systems for the synthesis and use of imaging agents
US-2025170282-A1 · May 29, 2025 · US
US9168317B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9168317-B2 |
| Application number | US-201113825372-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 23, 2011 |
| Priority date | Jun 21, 2010 |
| Publication date | Oct 27, 2015 |
| Grant date | Oct 27, 2015 |
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The present invention provides a method useful in the diagnosis and/or monitoring of mood disorders wherein there is an abnormal expression of PBR. The method of the invention is useful in the differential diagnosis of said mood disorders and other conditions where there is no abnormal expression of PBR but where the symptoms may be similar to those of said mood disorder.
Opening claim text (preview).
What is claimed is: 1. A method comprising the following steps: (a) administering to a subject of a mood disorder characterised by abnormal expression of peripheral benzodiazepine receptors (PBR) an in vivo imaging agent of Formula I: wherein: R 1 is C 1-3 alkyl or C 1-3 fluoroalkyl; R 2 is hydrogen, hydroxyl, halo, cyano, C 1-3 alkyl, C 1-3 alkoxy, C 1-3 flu…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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