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US-2024398571-A1 · Dec 5, 2024 · US
Drug eluting cochlear implants
US9162010B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9162010-B2 |
| Application number | US-201113284287-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 28, 2011 |
| Priority date | Nov 9, 2010 |
| Publication date | Oct 20, 2015 |
| Grant date | Oct 20, 2015 |
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Abstract
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Drug delivery systems and biocompatible coatings for use with implantable stimulation devices such as cochlear implants have been developed. These drug delivery systems and coatings comprise polyhydroxyalkanoate (PHA) polymers and copolymers. The drug delivery systems may be used to deliver pharmacologically active substances, for example, directly from a cochlear implant to the inner ear. The coatings can impart lubricity to cochlear devices for ease of insertion of the electrodes. In the preferred embodiment, the drug delivery system comprises a polyhydroxyalkanoate polymer, and in the most preferred embodiment, the PHA polymer comprises poly(4-hydroxybutyrate) (P(4HB)) or copolymer thereof. A particularly preferred embodiment is where the silicone sheath of the cochlear implant electrodes has been surface modified, and coated with P(4HB), and the P(4HB) either contains a pharmacologically active substance or has been coated with such a substance.
First claim
Opening claim text (preview).
We claim: 1. An implantable neural stimulation device comprising an outermost layer of a poly-4-hydroxybutyrate (P4HB) polymer-drug layer applied to-a plasma-activated silicone surface, wherein the P4HB-drug layer is smoother than the silicone surface, as measured by environmental Scanning electron microscopy. 2. The device of claim 1 , wherein a poly-4-hydroxybutyrate (P4HB) polymer undercoating is coated onto the silicone surface. 3. The…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US9162010B2 cover?
- Drug delivery systems and biocompatible coatings for use with implantable stimulation devices such as cochlear implants have been developed. These drug delivery systems and coatings comprise polyhydroxyalkanoate (PHA) polymers and copolymers. The drug delivery systems may be used to deliver pharmacologically active substances, for example, directly from a cochlear implant to the inner ear. The …
- Who is the assignee on this patent?
- Lenarz Thomas, Schmitz Klaus-Peter, Behrend Detlef, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification A61L27/34. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).