Crispr/cas-related methods and compositions for knocking out c5
US-2024415980-A1 · Dec 19, 2024 · US
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene
US9161995B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9161995-B2 |
| Application number | US-201213558101-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 25, 2012 |
| Priority date | Jul 25, 2011 |
| Publication date | Oct 20, 2015 |
| Grant date | Oct 20, 2015 |
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Abstract
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Nucleases and methods of using these nucleases for alteration of a CFTR gene and generation of cells and animal models.
First claim
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What is claimed is: 1. A protein comprising an engineered zinc finger protein DNA-binding domain, wherein the DNA-binding domain comprises four, five or six zinc finger recognition regions ordered F1 to F4, F1 to F5 or F1 to F6 from N-terminus to C-terminus, and wherein the protein is selected from the group consisting of: (i) a 5-finger zinc finger protein comprising the following recognition regions: F1: WPSCLYA (SEQ ID NO:8); F2: NGVLLKR (SEQ ID NO:9); F3: QSGNLAR (SEQ ID…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9161995B2 cover?
- Nucleases and methods of using these nucleases for alteration of a CFTR gene and generation of cells and animal models.
- Who is the assignee on this patent?
- Guschin Dmitry M, Holmes Michael C, Paschon David, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification A61K48/005. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).