Compact biosensor of matrix metalloproteinase with cadmium free quantum dots

US9155497B1 · US · B1

Patent metadata
FieldValue
Publication numberUS-9155497-B1
Application numberUS-201213487933-A
CountryUS
Kind codeB1
Filing dateJun 4, 2012
Priority dateJun 2, 2011
Publication dateOct 13, 2015
Grant dateOct 13, 2015

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Abstract

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The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.

First claim

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What is claimed is: 1. A quantum dot (QD) modified optical fiber-based biosensor system adapted for evaluation of metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS), said biosensor system comprising: (a) a multimode silica optical fiber comprising one or more quantum dots that (1) are bioconjugated on their surface to one or more peptides having an affinity for said metalloproteinase (MMP) enzyme, and (2) that are tethered to an ins…

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What does patent US9155497B1 cover?
The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.
Who is the assignee on this patent?
Plumley John B, Milligan Erin D, Osinski Marek, and 1 more
What technology area does this patent fall under?
Primary CPC classification A61B5/1455. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Oct 13 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).