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Role of ADAM10 and its relevance to disease and therapeutics
US9150865B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9150865-B2 |
| Application number | US-201113884502-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 9, 2011 |
| Priority date | Nov 9, 2010 |
| Publication date | Oct 6, 2015 |
| Grant date | Oct 6, 2015 |
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Abstract
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Certain embodiments are directed to compositions and methods of inhibiting pathogenic bacterial infection involving ADAMIO comprising administering an effective amount of a metalloprotease inhibitor to a patient. Certain embodiments are directed to method of inhibiting Staphylococcal infection comprising administering an effective amount of a metalloprotease inhibitor to a patient. Other embodiments concern methods of inhibiting infection by a bacteria from the genus Clostridium, Streptococcus, Listeria, Bacillus , or Arcanobacterium.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of inhibiting Staphylococcal infection comprising administering an effective amount of a metalloprotease inhibitor to a patient, wherein the patient has been determined to have or be at risk of developing a Staphylococcal infection, wherein the metalloprotease inhibitor is an inhibitor of A Disintegrin and Metalloprotease 10 (ADAM10), and inhibits ADAM10 activity by inhibiting an ADAM10 polypeptide. 2. The method of claim 1 , whe…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
- C12N15/1137Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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- What does patent US9150865B2 cover?
- Certain embodiments are directed to compositions and methods of inhibiting pathogenic bacterial infection involving ADAMIO comprising administering an effective amount of a metalloprotease inhibitor to a patient. Certain embodiments are directed to method of inhibiting Staphylococcal infection comprising administering an effective amount of a metalloprotease inhibitor to a patient. Other embodi…
- Who is the assignee on this patent?
- Bubeck Wardenburg Juliane, Univ Chicago
- What technology area does this patent fall under?
- Primary CPC classification C12N15/1137. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Oct 06 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).