Yeast display of proteins in the periplasmic space
US-2024102202-A1 · Mar 28, 2024 · US
Directed evolution using proteins comprising unnatural amino acids
US9150849B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9150849-B2 |
| Application number | US-29067308-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 31, 2008 |
| Priority date | Nov 2, 2007 |
| Publication date | Oct 6, 2015 |
| Grant date | Oct 6, 2015 |
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Abstract
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The invention provides methods and compositions for screening polypeptide libraries that include variants comprising unnatural amino acids. In addition, the invention provides vector packaging systems and methods for packaging a nucleic acid in a vector. Compositions of vectors produced by the methods and systems are also provided.
First claim
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What is claimed is: 1. A recombinant polypeptide expression library with normalized expression levels of a plurality of expressed polypeptide variants comprising unnatural amino acids, wherein the library is expressed from an expression vector, the library comprising: a) a plurality of expressed target polypeptide variants, wherein at least one of the expressed target polypeptide variants comprises at least one unnatural amino acid residue, and b) a packaging or specificity pol…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C12N15/1037Primary
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US9150849B2 cover?
- The invention provides methods and compositions for screening polypeptide libraries that include variants comprising unnatural amino acids. In addition, the invention provides vector packaging systems and methods for packaging a nucleic acid in a vector. Compositions of vectors produced by the methods and systems are also provided.
- Who is the assignee on this patent?
- Liu Chang, Tsao Meng-Lin, Smider Vaughn, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification C12N15/1037. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Oct 06 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).