Human antibodies against tissue factor and methods of use thereof

US9150658B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9150658-B2
Application numberUS-200913133811-A
CountryUS
Kind codeB2
Filing dateDec 9, 2009
Priority dateDec 9, 2008
Publication dateOct 6, 2015
Grant dateOct 6, 2015

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  2. Abstract

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  5. First independent claim

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Abstract

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Isolated human monoclonal antibodies which bind to human TF and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.

First claim

Opening claim text (preview).

The invention claimed is: 1. A human antibody which binds human Tissue Factor (TF), wherein said antibody: competes for TF binding with a reference antibody comprising a VH region comprising the sequence of SEQ ID NO:9 and a VL region comprising the sequence of SEQ ID NO:65, and does not compete for TF binding with a reference antibody comprising a VH region comprising the sequence of SEQ ID NO:37 and a VL region comprising the sequence of SEQ ID NO:93. 2.…

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What does patent US9150658B2 cover?
Isolated human monoclonal antibodies which bind to human TF and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.
Who is the assignee on this patent?
Verploegen Sandra, Satijn David P E, Hoet Rene, and 11 more
What technology area does this patent fall under?
Primary CPC classification C07K16/36. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Oct 06 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).