US9150499B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9150499-B2 |
| Application number | US-201113703758-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 14, 2011 |
| Priority date | Jun 14, 2010 |
| Publication date | Oct 6, 2015 |
| Grant date | Oct 6, 2015 |
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
What the patent document calls the invention.
A short plain-language summary of the technical disclosure.
Who owns or filed the patent and who is credited as inventor.
Filing, priority, publication, and grant dates set the timeline.
The legal scope of protection — read this for what is actually claimed.
Technology tags used to group this patent with similar filings.
Prior art links and similar publications in this corpus.
Official abstract text for this publication.
The present invention relates to a process for the preparation of substantially pure nateglinide of formula (I), substantially free from the cis-isomer and L-enantiomer and preparation of enantiomerically pure nateglinide form B, directly from the hydrolysis of a (−)-N-(trans-4-isopropylcyclohexyl-1-carbonyl)-D-phenylalanine alkyl ester in a ketonic solvent or water or mixture thereof.
Opening claim text (preview).
The invention claimed is: 1. A process for preparing nateglinide of formula (I) or a pharmaceutically-acceptable salt thereof, wherein the nateglinide is polymorphic Form B, which process comprises: preparing (−)-N-(trans-4-isopropylcyclohexyl-1-carbonyl)-D-phenylalanine alkyl ester of formula (II) by condensation of a D-phenylalanine alkyl ester of formula (IV) or an acid addition salt thereof with trans-4-isopropyl-cyclohexylcarboxylic acid of formula (III) in the presence of a c…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Related publications grouped by family.
Free tools are coming soon. Tell us what you want to track and we'll notify you.
Answers are generated from the same data shown on this page.