Inhibitors of tyk2
US-2024425484-A1 · Dec 26, 2024 · US
US9145367B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9145367-B2 |
| Application number | US-201013377760-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 14, 2010 |
| Priority date | Jun 12, 2009 |
| Publication date | Sep 29, 2015 |
| Grant date | Sep 29, 2015 |
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Official abstract text for this publication.
The present invention relates to compound Formula (I) wherein: Formula (II) means a pyridazine, a pyrimidine or a pyrazine group, R independently represent a hydrogen atom, a halogen atom or a group chosen among a CN group, a hydroxyl group, a COOR 1 group, a (C 1 -C 3 )fluoroalkyl group, a (C 1 -C 3 )fluoroalkoxy group, a NO 2 group, a NR 1 R 2 group, a (C 1 -C 4 )alkoxy group, a phenoxy group and a (C 1 -C 3 )alkyl group, said alkyl being optionally mono-substituted by a hydroxyl group, n is 1, 2 or 3, n is 1 or 2, R is a hydrogen atom, a halogen atom or a group chosen among a (C 1 -C 3 )alkyl group, a hydroxyl group, a COOR 1 group, a NO 2 group, a NR 1 R 2 group, a morpholinyl or a morpholino group, a N-methylpiperazinyl group, a (C 1 -C 3 )fluoroalkyl group, a (C 1 -C 4 )alkoxy group and a CN group, Z is N or C, Y is N or C, X is N or C, W is N or C, T is N or C, U is N or C, for use as an agent for preventing, inhibiting or treating AIDS. Some of said compounds are new and also form part of the invention.
Opening claim text (preview).
The invention claimed is: 1. A method of inhibiting replication of HIV-1 in a patient infected with HIV-1 comprising administering to a patient in need thereof an effective quantity of at least one compound of formula (I) or a pharmaceutically acceptable salt thereof to thereby inhibit replication of HIV-1: wherein:…
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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