Process for preparing [(3-hydroxypyridine-2-carbonyl)amino]alkanoic acids, esters and amides

US9145366B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9145366-B2
Application numberUS-201213488554-A
CountryUS
Kind codeB2
Filing dateJun 5, 2012
Priority dateJun 6, 2011
Publication dateSep 29, 2015
Grant dateSep 29, 2015

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Abstract

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Disclosed are processes for preparing [(3-hydroxypyridine-2-carbonyl)amino]-alkanoic acids, derivatives, inter alia, 5-aryl substituted and 5-heteroaryl substituted [(3-hydroxypyridine-2-carbonyl]amino}acetic acids. Further disclosed are methods for making prodrugs of [(3-hydroxypyridine-2-carbonyl)-amino]acetic acids, for example, [(3-hydroxypyridine-2-carbonyl]amino}acetic acid esters and {[3-hydroxypyridine-2-carbonyl]amino}acetic acid amides. The disclosed compounds are useful as prolyl hydroxylase inhibitors or for treating conditions wherein prolyl hydroxylase inhibition is desired.

First claim

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What is claimed is: 1. A process for preparing a compound having the formula: wherein R 1 is chosen from: L is a linking unit having the formula: —(CR 7a R 7b ) n…

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What does patent US9145366B2 cover?
Disclosed are processes for preparing [(3-hydroxypyridine-2-carbonyl)amino]-alkanoic acids, derivatives, inter alia, 5-aryl substituted and 5-heteroaryl substituted [(3-hydroxypyridine-2-carbonyl]amino}acetic acids. Further disclosed are methods for making prodrugs of [(3-hydroxypyridine-2-carbonyl)-amino]acetic acids, for example, [(3-hydroxypyridine-2-carbonyl]amino}acetic acid esters and {[3…
Who is the assignee on this patent?
Lanthier Christopher M, Gorin Boris, Oudenes Jan, and 5 more
What technology area does this patent fall under?
Primary CPC classification C07D213/79. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Sep 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).