Blends containing proteases
US-2016319268-A1 · Nov 3, 2016 · US
Compositions and methods for inhibiting matrix metalloproteinase (MMP)-mediated cell migration
US9133239B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9133239-B2 |
| Application number | US-201113642078-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 19, 2011 |
| Priority date | Apr 20, 2010 |
| Publication date | Sep 15, 2015 |
| Grant date | Sep 15, 2015 |
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Abstract
Official abstract text for this publication.
The invention provides peptides, portions and derivatives thereof, that are useful for reducing cell migration, and for reducing symptoms of pathological diseases that are associated with undesirable cell migration, and in particular MMP-induced cell migration. This invention also provides peptides that are useful for detecting (e.g., imaging) cancers.
First claim
Opening claim text (preview).
We claim: 1. A method for reducing one or more symptoms of a disease associated with cell expression of a matrix metalloproteinase (MMP), comprising a) providing i) a mammalian subject in need of reducing one or more symptoms of said disease, and ii) a composition comprising a purified polypeptide that contains an amino acid sequence selected from the group consisting of GYPMP (SEQ ID NO:04), VMDGYPMP (SEQ ID NO:01), and GYPKSALR (SEQ ID NO:03), wherein said polypeptide does no…
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Classifications
Human Necessities · mapped topic
- C12N9/6491Primary
Chemistry & Metallurgy · mapped topic
- C07K7/06Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US9133239B2 cover?
- The invention provides peptides, portions and derivatives thereof, that are useful for reducing cell migration, and for reducing symptoms of pathological diseases that are associated with undesirable cell migration, and in particular MMP-induced cell migration. This invention also provides peptides that are useful for detecting (e.g., imaging) cancers.
- Who is the assignee on this patent?
- Cao Jian, Dufour Antoine, Univ New York State Res Found
- What technology area does this patent fall under?
- Primary CPC classification C12N9/6491. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).