Therapy prediction and optimization of serum potassium for renal failure blood therapy, especially home hemodialysis

US9132219B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9132219-B2
Application numberUS-201313969162-A
CountryUS
Kind codeB2
Filing dateAug 16, 2013
Priority dateApr 16, 2010
Publication dateSep 15, 2015
Grant dateSep 15, 2015

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

A method of predicting serum potassium concentrations in a patient during hemodialysis includes measuring serum potassium concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the treatment session and estimating a potassium mobilization clearance and a pre-dialysis distribution volume of potassium for the patient. Serum potassium concentrations of the patient can then be predicted at any time during any hemodialysis treatment session with the estimated potassium mobilization clearance and pre-dialysis distribution volume of potassium of the patient.

First claim

Opening claim text (preview).

The invention is claimed as follows: 1. A method of predicting serum potassium concentrations in a patient during hemodialysis and determining a treatment regimen based thereon, the method comprising: measuring serum potassium concentrations (“C”) of the patient over a hemodialysis treatment session time and an ultrafiltration rate (“Q UF ”) calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the treatment session; estimating K M and V PRE for the patient using a non-linear least squares fitting to the equations: C ⁡ ( t ) = C PRE [ K M + DC D / C PRE K M + K R + D - Q UF +   [ 1 - K M + DC D / C PRE K M + K R + D - Q UF ] × [ V ⁡ ( t ) V PRE ] K M + K R + D - Q UF Q UF ] , ⁢ ⁢ and ( eqn . ⁢ 1 ⁢ - ⁢ A ) ⁢ C ⁡ ( T ) = C PRE -

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Classifications

  • Physics · mapped topic

  • Physical characteristics of the blood, e.g. haematocrit, urea · CPC title

  • Weight of the patient · CPC title

  • A61M1/16Primary

    with membranes · CPC title

  • Profiling or modelling of patient or predicted treatment evolution or outcome · CPC title

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What does patent US9132219B2 cover?
A method of predicting serum potassium concentrations in a patient during hemodialysis includes measuring serum potassium concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the…
Who is the assignee on this patent?
Baxter Int, Baxter Healthcare Sa, Baxter Healthcare Sa
What technology area does this patent fall under?
Primary CPC classification A61M1/16. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).