CD8+ t cell based immunosuppressive tumor microenvironment detection method
US-11881286-B2 · Jan 23, 2024 · US
US9119829B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9119829-B2 |
| Application number | US-201313782421-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 1, 2013 |
| Priority date | Sep 3, 2010 |
| Publication date | Sep 1, 2015 |
| Grant date | Sep 1, 2015 |
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Methods, systems, and compositions related to generating and using a solution rich in interleukin-1 receptor antagonist are provided. Methods include contacting a liquid comprising white blood cells with a solid extraction material and stimulating with an electromagnetic field to activate production of interleukin-1 receptor antagonist. The interleukin-1 receptor antagonist can be separated from the solid extraction material. Methods for treating a site of inflammation in a patient include administering the solution rich in interleukin-1 receptor antagonist to the site of inflammation.
Opening claim text (preview).
What is claimed is: 1. A method for generating a solution rich in interleukin-1 receptor antagonist comprising: (a) contacting a liquid comprising white blood cells with a solid extraction material, wherein the solid extraction material activates the white blood cells to generate interleukin-1 receptor antagonist, and wherein the solid extraction material comprises a member selected from the group consisting of corundum, quartz, titanium, dextran, agarose, polystyrene, polyethylen…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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