Live attenuated bordetella strains as a single dose vaccine against whooping cough

US9119804B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9119804-B2
Application numberUS-22489507-A
CountryUS
Kind codeB2
Filing dateMar 7, 2007
Priority dateMar 10, 2006
Publication dateSep 1, 2015
Grant dateSep 1, 2015

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Abstract

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A mutated Bordetella strain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection. Use of the attenuated Bordetella strain for the manufacture of a vaccine or immunogenic composition, as well as methods for protecting mammals against infection by Bordetella are also provided.

First claim

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The invention claimed is: 1. A triple mutated Bordetella strain which is a BPZE1 strain deposited with the Collection Nationale de Culture Microorganismes (C.N.C.M.) on Mar. 9, 2006, under number 1-3585. 2. An immunogenic composition comprising the attenuated mutated Bordetella strain according to claim 1 . 3. The immunogenic composition according to claim 2 , further comprising a pharmaceutically suitable excipient, vehicle and/or carr…

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What does patent US9119804B2 cover?
A mutated Bordetella strain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection. Use of the attenuated Bordetella strain for the manufacture of a vaccine or immunogenic compos…
Who is the assignee on this patent?
Locht Camille, Mielcarek Nathalie, Debrie Anne-Sophie, and 4 more
What technology area does this patent fall under?
Primary CPC classification A61K39/099. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Sep 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).