Pharmaceutical combination and use thereof
US-2024189341-A1 · Jun 13, 2024 · US
US9119804B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9119804-B2 |
| Application number | US-22489507-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 7, 2007 |
| Priority date | Mar 10, 2006 |
| Publication date | Sep 1, 2015 |
| Grant date | Sep 1, 2015 |
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A mutated Bordetella strain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection. Use of the attenuated Bordetella strain for the manufacture of a vaccine or immunogenic composition, as well as methods for protecting mammals against infection by Bordetella are also provided.
Opening claim text (preview).
The invention claimed is: 1. A triple mutated Bordetella strain which is a BPZE1 strain deposited with the Collection Nationale de Culture Microorganismes (C.N.C.M.) on Mar. 9, 2006, under number 1-3585. 2. An immunogenic composition comprising the attenuated mutated Bordetella strain according to claim 1 . 3. The immunogenic composition according to claim 2 , further comprising a pharmaceutically suitable excipient, vehicle and/or carr…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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