Compound calibrator for thermal sensors

US9109961B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9109961-B2
Application numberUS-201113223270-A
CountryUS
Kind codeB2
Filing dateAug 31, 2011
Priority dateAug 31, 2010
Publication dateAug 18, 2015
Grant dateAug 18, 2015

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  2. Abstract

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Abstract

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The present invention, in one aspect, provides a method for calibrating thermal control elements in situ using a single compound calibrator. In some embodiments, the present invention uses a compound calibrator to calibrate thermal control elements on a microfluidic device. In non-limiting embodiment, the compound calibrator can be a droplet, plug, slug, segment or continuous flow of any appropriate solution that, when heated, yields a thermal response profile with a plurality of features (e.g., maxima, minima, inflection points, linear regions, etc.).

First claim

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What is claimed is: 1. A method for calibrating a thermal control element, comprising: providing a compound calibrator in thermal contact with said thermal control element, wherein the compound calibrator is a mixture of two or more amplicons of a nucleic acid; utilizing said thermal control element to perform a thermal variation on said compound calibrator to generate a thermal response profile for said compound calibrator; identifying a first feature of said thermal response…

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What does patent US9109961B2 cover?
The present invention, in one aspect, provides a method for calibrating thermal control elements in situ using a single compound calibrator. In some embodiments, the present invention uses a compound calibrator to calibrate thermal control elements on a microfluidic device. In non-limiting embodiment, the compound calibrator can be a droplet, plug, slug, segment or continuous flow of any approp…
Who is the assignee on this patent?
Coursey Johnathan S, Hasson Kenton C, Canon Us Life Sciences Inc
What technology area does this patent fall under?
Primary CPC classification G01K15/00. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).